Mammalian DNA methylome dynamics: mechanisms, functions and new frontiers

A Wei, H Wu - Development, 2022 - journals.biologists.com
… and functions of DNA methylome in mammalian … methylome sequencing and epigenome
editing tools, in dissecting the mechanistic relationship between methylation dynamics

Longitudinal personal DNA methylome dynamics in a human with a chronic condition

R Chen, L Xia, K Tu, M Duan, K Kukurba… - Nature medicine, 2018 - nature.com
… transcriptomes and personal DNA methylomes displayed distinct dynamics that associate
with … more dynamic and acute health conditions, whereas the PBMC DNA methylome profiles …

[PDF][PDF] Single-cell DNA methylome sequencing and bioinformatic inference of epigenomic cell-state dynamics

M Farlik, NC Sheffield, A Nuzzo, P Datlinger… - Cell reports, 2015 - cell.com
methylomes to infer cell-state dynamics. Using these technological advances, we studied
epigenomic cell-state dynamics in … The DNA methylome data reported in this paper have been …

Spatiotemporal DNA methylome dynamics of the developing mouse fetus

Y He, M Hariharan, DU Gorkin, DE Dickel, C Luo… - Nature, 2020 - nature.com
… Developing fetal tissue methylomes To assess the cytosine DNA methylation landscape
in the developing mouse embryo, we generated 168 methylomes to cover most of the major …

Dynamics of DNA methylomes underlie oyster development

G Riviere, Y He, S Tecchio, E Crowell, M Gras… - PLoS …, 2017 - journals.plos.org
… This study shows that DNA methylome dynamics underlie development through transcription
regulation in the oyster, a lophotrochozoan species. To our knowledge, this is the first …

The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer

AF Fernandez, C Rosales, P Lopez-Nieva… - Genome …, 2009 - genome.cshlp.org
… of the HPV16, HPV18, and HBV viruses and the DNA … the dynamic changes in the viral
DNA methylome and their … of the HBV DNA methylome and to confirm its dynamic nature, we …

Dynamic DNA methylation: In the right place at the right time

C Luo, P Hajkova, JR Ecker - Science, 2018 - science.org
… type–specific patterns and pervasive dynamics during mammalian development. Here we
… Beyond the newly appreciated dynamics, regulatory roles for 5mC have been suggested in …

Analysis of the DNA methylome and transcriptome in granulopoiesis reveals timed changes and dynamic enhancer methylation

M Rönnerblad, R Andersson, T Olofsson… - Blood, The Journal …, 2014 - ashpublications.org
… In this study, we investigated the DNA methylome and transcriptome of human cells in 4
separate differentiation stages in granulopoiesis, ranging from the multipotent common myeloid …

Targeted bisulfite sequencing of the dynamic DNA methylome

MJ Ziller, EK Stamenova, H Gu, A Gnirke… - Epigenetics & …, 2016 - Springer
Background The ability to measure DNA methylation precisely and efficiently continues to
drive our understanding of this modification in development and disease. Whole genome …

[HTML][HTML] Developmental functions of the dynamic DNA methylome and hydroxymethylome in the mouse and zebrafish: similarities and differences

P Jessop, A Ruzov, M Gering - Frontiers in Cell and Developmental …, 2018 - frontiersin.org
… In the following text, we will describe the early developmental differences in the dynamics
of the methylome and hydroxymethylome in mice and zebrafish. The divergent phenotypes …