… Our results show that the DNA methylome of monocytes changes in a dynamic … the DNA
methylome of peripheral blood monocytes. To confirm the plasticity of the monocyte methylome …

… these inflammatory cytokines in the acquisition of DNA methylation … Altogether, this analysis
suggested that the DNA methylation … to those observed in relation to inflammatory cytokines. …

… RA by producing key cytokines, small molecule mediators and proteases.5 Rheumatoid FLS
exhibit a unique aggressive phenotype that could contribute to the cytokine milieu and joint …

… However, simultaneous to the overactivated pro-inflammatory cytokines found in the sepsis
groups, we also report DNA methylation changes involving the anti-inflammatory cytokines. …

… sustained inflammatory process in the synovial tissue characterized by proinflammatory
cytokines … Furthermore, we explored the predictive features of the DNA methylome in a large RA …

… DNA methylomes with respect to those from healthy controls, affecting critical monocyte-related
genes. DNA … downstream to toll-like receptors and inflammatory cytokines. In fact, in vitro …

… Broad changes to the DNA methylome also occur with age, and … CpG sites related to
inflammatory cytokines in our study (TNF, 7/… Regarding the anti-inflammatory cytokine IL-10, of the …

… Inflammation can be reduced with drugs that inhibit proinflammatory cytokines. …
inflammatory cytokines or anti-inflammatory cytokines and other interleukins are involved with …

… In the present study we have analyzed the circulating methylome of RA patients to identify
the presence of methylation variation associated with TNFi response. Compared to previous …

… -stimulated expression of the proinflammatory cytokine TNFα together with a significant …
-inflammatory cytokine IL-10 by SAM, suggesting a wide-ranging effect of SAM on inflammation. …