… Regulatory DNA sequences in vertebrates often … DNA is catalyzed by DNA methyltransferases
(DNMTs), which play a special role in the initiation of chromatin remodeling and gene …

… Gene targeting in embryonic stem (ES) cells has been used to mutate the murine DNA
methyltransferase gene. ES cell lines homozygous for the mutation were generated by …

… DNA methylation is an important component of the epigenetic control of genome functions. …
the DNA Methyltransferase (dnmt1) gene expression is critical for comprehending how DNA …

… ICF syndrome is the only genetic disorder known to involve constitutive abnormalities of …
have mutations in both alleles of the gene that encodes DNA methyltransferase 3B (refs 5, 6). …

… local increases in DNA methylation that hold potential for gene inactivation events. To study
… human DNA methyltransferase gene that codes for the enzyme catalyzing DNA methylation. …

… shown that DNA methylation activity correlates with the proliferative activity of cells (8-10).
In this report, we test the hypothesis that regulation of DNA methyltransferase gene expression …

… gene, which encodes a protein that binds to methylated DNA. … in the DNA methyltransferase-1
(Dnmt1) gene has shown that … that result from mutations in DNA methyltransferase genes. …

… are caused by mutations in DNA methyltransferase genes. … with mutations in DNA
methyltransferase genes have largely … likelihood that the DNA methyltransferase mutations will …

… homologies to known DNA methyltransferases, we identified a genomic sequence in the
ICF region that contains the homologue of the mouse Dnmt3b methyltransferase gene. Using …

… While the details of the molecular and cellular basis of dDnmt2 being a longevity gene …
DNA methyltransferase gene family. Namely, a threshold level of expression of dDnmt2, a gene …