… DNA methyltransferases or DNMT's. I will then discuss the role of methylation in genetic
disease and cancer … one of the best studied DNA methyltransferases and why these interactions …

DNA methyltransferases are an essential class of modifiers in epigenetics. In mammals,
DNMT1, DNMT3A and DNMT3B participate in DNA methylation to regulate normal biological …

… The maintenance DNA methyltransferase (DNMT) 1 and the de novo methyltransferases …
promoter region with de novo DNA methyltransferase DNMT3B and promotes differentiation-…

… DNA methyltransferases are the enzymes … of DNA methyltransferases may contribute to
tumor progression through methylation-mediated gene inactivation in various human cancers. …

… Here, we describe the aberrant DNA methylation changes in human cancers and how they
… DNA hypermethylation-based gene silencing, human cancers also display gene body DNA …

… DNA methyltransferases (DNMT) (1,2). The structures and catalytic mechanisms of DNA
methyltransferases … mammals; thus, DNA methylation is the most prevalent DNA modification (3). …

… several significant human diseases including various cancers, neuron disorder, psychosis,
… of DNA methyltransferases (DNMTs) [9–13]. DNMTs are the enzymes responsible for DNA …

… directly at the DNA level. Consequently, in this review, we will focus on the role of DNA
methyltransferase inhibitors in the further development of epigenetic cancer therapies. We also …

… to methyltransferase-facilitated deamination. Support for a role of DNA methyltransferase
as a mutator enzyme is provided by work with a prokaryotic DNA methyltransferase under S-…

… of treating cancer by reducing DNA methyltransferase activity… the mouse Dnmt1 DNA
methyltransferase strongly suppress … and DNMT3B DNA methyltransferases in human cancer cells …