Aerobic exercise training as a potential cardioprotective strategy to attenuate doxorubicin-induced cardiotoxicity

SA Kouzi, MN Uddin - Journal of Pharmacy & …, 2016 - journals.library.ualberta.ca
treating and/or preventing doxorubicin-induced cardiotoxicity. Of these potential strategies,
aerobic exercise … that aerobic exercise training, administered prior to, during and/or following …

Concomitant low-dose doxorubicin treatment and exercise

K Sturgeon, K Schadler… - American Journal …, 2014 - journals.physiology.org
… Cardiotoxicity is a side effect for cancer patients treated with doxorubicin (DOX). We tested
the hypothesis that low-intensity aerobic exercise concomitant with DOX treatment would …

Aerobic exercise during early murine doxorubicin exposure mitigates cardiac toxicity

F Wang, B Iskra, E Kleinerman… - Journal of pediatric …, 2018 - journals.lww.com
… Interestingly, moderate aerobic exercise during Doxo treatment significantly mitigated
decreases in ejection fraction and fractional shortening. In contrast, these protective effects of …

[HTML][HTML] Early moderate intensity aerobic exercise intervention prevents doxorubicin-caused cardiac dysfunction through inhibition of cardiac fibrosis and inflammation

HL Yang, PL Hsieh, CH Hung, HC Cheng, WC Chou… - Cancers, 2020 - mdpi.com
… new evidence that exercise still has positive effects on cancer treatment if they … that exercise
still has positive effects on cancer treatment if they have not been preconditioned to exercise

[HTML][HTML] Cardiotoxicity of doxorubicin treatment and physical activity: a systematic review

TN Maia, GBR Araujo, JAC Teixeira… - International Journal of …, 2017 - SciELO Brasil
… As described in Chart 1, all studies included in this review evaluated the capacity of aerobic
exercises to provide cardioprotection against DOX adverse effects. Therefore, the following …

[PDF][PDF] Cardioprotective effects of aerobic regular exercise against doxorubicin-induced oxidative stress in rat

J Ashrafi, V Dabidi Roshan, S Mahjoub - Afr J Pharm Pharmacol, 2012 - academia.edu
… The authors reported that aerobic exercise results in many types of physiological (vascular, …
cardioprotection induced by aerobic regular exercise in hearts from DOX treated rats was …

The effect of an aerobic exercise bout 24 h prior to each doxorubicin treatment for breast cancer on markers of cardiotoxicity and treatment symptoms: a RCT

AA Kirkham, ND Eves, RE Shave, KA Bland… - … research and treatment, 2018 - Springer
… The exercise bout also … exercise session 24 h prior to doxorubicin treatment by determining
the cumulative effect of performing this intervention prior to every doxorubicin treatment

Modulatory effect of aerobic exercise training on doxorubicin-induced cardiotoxicity in rats with different ages

M Ahmadian, V Dabidi Roshan - Cardiovascular Toxicology, 2018 - Springer
… to doxorubicin treatment could be useful in minimizing toxicity after chemotherapy with
doxorubicin … Future studies examining the exercise-induced changes and age-related differences …

Both aerobic exercise and resveratrol supplementation attenuate doxorubicin-induced cardiac injury in mice

VW Dolinsky, KJ Rogan, MM Sung… - American Journal …, 2013 - journals.physiology.org
… Although clinical evidence suggests that aerobic exercise training (ET) can prevent … the
efficacy of modest ET to RESV treatment on exercise performance, LV remodeling, and oxidative …

Physical exercise prior and during treatment reduces sub-chronic doxorubicin-induced mitochondrial toxicity and oxidative stress

I Marques-Aleixo, E Santos-Alves, D Mariani… - Mitochondrion, 2015 - Elsevier
… that exercise performed prior to DOX treatmentexercise models (endurance treadmill
training—TM and voluntary free-wheel activity—FW) when used prior and during DOX treatment. …