Dynamic heterogeneity and DNA methylation in embryonic stem cells
… abrupt, step-like dynamics due to cell state transitions and transcriptional bursts. Finally,
using perturbations, we observed that DNA methylation modulates the population fraction of …
using perturbations, we observed that DNA methylation modulates the population fraction of …
Dynamic enhancer DNA methylation as basis for transcriptional and cellular heterogeneity of ESCs
Y Song, PR van den Berg, S Markoulaki, F Soldner… - Molecular cell, 2019 - cell.com
… DNA methylation at the … Dynamic allele-specific DNA methylation at the two SEs was also
seen at different stages in preimplantation embryos, revealing that methylation heterogeneity …
seen at different stages in preimplantation embryos, revealing that methylation heterogeneity …
Dynamic DNA methylation: In the right place at the right time
The classical model of cytosine DNA methylation (the … patterns and pervasive dynamics during
mammalian development. … Beyond the newly appreciated dynamics, regulatory roles for …
mammalian development. … Beyond the newly appreciated dynamics, regulatory roles for …
Stochastic modeling reveals kinetic heterogeneity in post-replication DNA methylation
… the genome on newly-formed DNA shortly after replication. In … rate at which DNA methylation
appears on nascent DNA post … a window is dynamic and temporally heterogeneous within a …
appears on nascent DNA post … a window is dynamic and temporally heterogeneous within a …
The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space
… To investigate the DNA methylation dynamics associated with glioblastoma disease
progression, we established a richly annotated dataset of patients with primary glioblastoma (IDH-…
progression, we established a richly annotated dataset of patients with primary glioblastoma (IDH-…
Dynamics and context-dependent roles of DNA methylation
C Ambrosi, M Manzo, T Baubec - Journal of molecular biology, 2017 - Elsevier
… DNA methylation and how this modification is regulated and discusses the dynamics of
genome-wide DNA methylation … to be clarified if heterogeneity of DNA methylation at these sites …
genome-wide DNA methylation … to be clarified if heterogeneity of DNA methylation at these sites …
An integrative multi-scale analysis of the dynamic DNA methylation landscape in aging
… By using a powerful algorithm to correct for cellular heterogeneity [15], we demonstrate that
most of the epigenetic drift, specially the age-hypermethylated component of it, is not caused …
most of the epigenetic drift, specially the age-hypermethylated component of it, is not caused …
Longitudinal DNA methylation dynamics as a practical indicator in clinical epigenetics
… In the present study, broader odds ratios of dynamic CpGs and significant between-study
heterogeneity in these traits were observed among all four samples, also implying the higher …
heterogeneity in these traits were observed among all four samples, also implying the higher …
Dynamic heterogeneity of DNA methylation and hydroxymethylation in embryonic stem cell populations captured by single-cell 3D high-content analysis
J Tajbakhsh, D Stefanovski, G Tang… - Experimental cell …, 2015 - Elsevier
… of chromatin structure and relevant DNA expression in cellular … DNA methylation increased
in a linear fashion. As a result of this development we had observed distinct DNA methylation …
in a linear fashion. As a result of this development we had observed distinct DNA methylation …
Modeling DNA methylation profiles through a dynamic equilibrium between methylation and demethylation
… pattern of DNA methylation was the result of a dynamic balance between DNA methylation
and … Despite the presence of this heterogeneity among cells, we and others described that the …
and … Despite the presence of this heterogeneity among cells, we and others described that the …
相关搜索
- kinetic heterogeneity dna methylation
- dna methylation patterns
- stem cells dna methylation
- gene expression dna methylation
- dna methylation variability
- dna methylation data
- dna methylation profiles
- single cell resolution dna methylation
- dna methylation landscape
- dna methylation and hydroxymethylation dynamic heterogeneity
- clinical epigenetics dna methylation dynamics
- early human development dna methylation dynamics
- functional annotation dna methylation dynamics
- right place dynamic dna methylation
- stability of dna methylation intraindividual dynamics
- enhancer dna methylation cellular heterogeneity