Dynamic reprogramming of DNA methylation in the early mouse embryo
Dynamic epigenetic modification of the genome occurs during early development of the
mouse. Active demethylation of the paternal genome occurs in the zygote, followed by passive …
mouse. Active demethylation of the paternal genome occurs in the zygote, followed by passive …
Dynamic reprogramming of DNA methylation at an epigenetically sensitive allele in mice
ME Blewitt, NK Vickaryous, A Paldi, H Koseki… - PLoS …, 2006 - journals.plos.org
… To this end, we have analysed the DNA methylation state of the A vy allele in gametes, …
We found that DNA methylation at the LTR of the IAP at the A vy allele is reprogrammed in early …
We found that DNA methylation at the LTR of the IAP at the A vy allele is reprogrammed in early …
Dynamics and Mechanisms of DNA Methylation Reprogramming
S Pennings, A Revuelta, KA McLaughlin… - Epigenetics and …, 2019 - Elsevier
… However, charting the dynamics of DNA methylation suggests that mouse blastocysts are
significantly hypomethylated, implying that DNA methylation is also required for post-blastocyst …
significantly hypomethylated, implying that DNA methylation is also required for post-blastocyst …
Dynamic DNA methylation: In the right place at the right time
… At distal regulatory elements, 5mC can either prohibit the binding of 5mC-sensitive TFs or
interact with TFs that show a preference for methylated binding sequence. DNA methylation at …
interact with TFs that show a preference for methylated binding sequence. DNA methylation at …
[HTML][HTML] Dynamic reprogramming of DNA methylation in SETD2-deregulated renal cell carcinoma
Clear cell renal cell carcinomas (ccRCCs) harbor frequent mutations in epigenetic modifiers
including SETD2, the H3K36me3 writer. We profiled DNA methylation (5mC) across the …
including SETD2, the H3K36me3 writer. We profiled DNA methylation (5mC) across the …
DNA methylation reprogramming during mammalian development
Y Zeng, T Chen - Genes, 2019 - mdpi.com
… DNA methylation patterns upon implantation. In this review, we discuss the highly dynamic
and regulated processes of DNA … regulators that are involved in these reprogramming events. …
and regulated processes of DNA … regulators that are involved in these reprogramming events. …
DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos
DM Messerschmidt, BB Knowles… - Genes & …, 2014 - genesdev.cshlp.org
… At present, our knowledge of epigenetic reprogramming is accumulating at a dizzying pace.
… epigenetic dynamics during the mammalian life cycle, with a focus on DNA methylation and …
… epigenetic dynamics during the mammalian life cycle, with a focus on DNA methylation and …
Dynamic regulation of DNA methylation during mammalian development
S Guibert, T Forné, M Weber - Epigenomics, 2009 - Taylor & Francis
… reprogramming. In this review, we will discuss the distribution and function of DNA methylation
in … DNA methylation reprogramming occurring in early embryos and primordial germ cells. …
in … DNA methylation reprogramming occurring in early embryos and primordial germ cells. …
The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells
… Genome-wide DNA methylation reprogramming occurs in mouse primordial germ cells (PGCs)
and preimplantation embryos, but the precise dynamics and biological outcomes are …
and preimplantation embryos, but the precise dynamics and biological outcomes are …
DNA methylation dynamics during the mammalian life cycle
JA Hackett, MA Surani - … of the Royal Society B: Biological …, 2013 - royalsocietypublishing.org
… of DNA methylation biology including its dynamic distribution … the role of CpG methylation
in regulating gene transcription … of the dynamics and roles of DNA methylation during the …
in regulating gene transcription … of the dynamics and roles of DNA methylation during the …
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