Dynamic reprogramming of DNA methylation in the early mouse embryo

F Santos, B Hendrich, W Reik, W Dean - Developmental biology, 2002 - Elsevier
Dynamic epigenetic modification of the genome occurs during early development of the
mouse. Active demethylation of the paternal genome occurs in the zygote, followed by passive …

Dynamic reprogramming of DNA methylation at an epigenetically sensitive allele in mice

ME Blewitt, NK Vickaryous, A Paldi, H Koseki… - PLoS …, 2006 - journals.plos.org
… To this end, we have analysed the DNA methylation state of the A vy allele in gametes, …
We found that DNA methylation at the LTR of the IAP at the A vy allele is reprogrammed in early …

Dynamics and Mechanisms of DNA Methylation Reprogramming

S Pennings, A Revuelta, KA McLaughlin… - Epigenetics and …, 2019 - Elsevier
… However, charting the dynamics of DNA methylation suggests that mouse blastocysts are
significantly hypomethylated, implying that DNA methylation is also required for post-blastocyst …

Dynamic DNA methylation: In the right place at the right time

C Luo, P Hajkova, JR Ecker - Science, 2018 - science.org
… At distal regulatory elements, 5mC can either prohibit the binding of 5mC-sensitive TFs or
interact with TFs that show a preference for methylated binding sequence. DNA methylation at …

[HTML][HTML] Dynamic reprogramming of DNA methylation in SETD2-deregulated renal cell carcinoma

RL Tiedemann, RA Hlady, PD Hanavan, DF Lake… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Clear cell renal cell carcinomas (ccRCCs) harbor frequent mutations in epigenetic modifiers
including SETD2, the H3K36me3 writer. We profiled DNA methylation (5mC) across the …

DNA methylation reprogramming during mammalian development

Y Zeng, T Chen - Genes, 2019 - mdpi.com
DNA methylation patterns upon implantation. In this review, we discuss the highly dynamic
and regulated processes of DNA … regulators that are involved in these reprogramming events. …

DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos

DM Messerschmidt, BB Knowles… - Genes & …, 2014 - genesdev.cshlp.org
… At present, our knowledge of epigenetic reprogramming is accumulating at a dizzying pace.
… epigenetic dynamics during the mammalian life cycle, with a focus on DNA methylation and …

Dynamic regulation of DNA methylation during mammalian development

S Guibert, T Forné, M Weber - Epigenomics, 2009 - Taylor & Francis
reprogramming. In this review, we will discuss the distribution and function of DNA methylation
in … DNA methylation reprogramming occurring in early embryos and primordial germ cells. …

The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells

S Seisenberger, S Andrews, F Krueger, J Arand… - Molecular cell, 2012 - cell.com
… Genome-wide DNA methylation reprogramming occurs in mouse primordial germ cells (PGCs)
and preimplantation embryos, but the precise dynamics and biological outcomes are …

DNA methylation dynamics during the mammalian life cycle

JA Hackett, MA Surani - … of the Royal Society B: Biological …, 2013 - royalsocietypublishing.org
… of DNA methylation biology including its dynamic distribution … the role of CpG methylation
in regulating gene transcription … of the dynamics and roles of DNA methylation during the …