Enhancers and super-enhancers have an equivalent regulatory role in embryonic stem cells through regulation of single or multiple genes
SD Moorthy, S Davidson, VM Shchuka… - Genome …, 2017 - genome.cshlp.org
… enhancer clusters (ECs) and isolated enhancers in mouse embryonic stem (ES) cells…
Our results reveal that the effect of deleting ECs, also classified as ES cell super-enhancers, …
Our results reveal that the effect of deleting ECs, also classified as ES cell super-enhancers, …
Super enhancers
H Stower - Nature reviews Genetics, 2013 - nature.com
… In these two studies, the authors identified a subset of enhancers termed 'super enhancers',
… pluripotent state in embryonic stem cells (ESCs). They bind enhancers along with Mediator …
… pluripotent state in embryonic stem cells (ESCs). They bind enhancers along with Mediator …
[HTML][HTML] Investigating the role of super-enhancer RNAs underlying embryonic stem cell differentiation
… Although super-enhancers play a critical role in the core transcriptional regulatory circuity
of embryonic stem cell (ESC) differentiation, whether seRNAs have similar properties should …
of embryonic stem cell (ESC) differentiation, whether seRNAs have similar properties should …
[HTML][HTML] YY1 positively regulates transcription by targeting promoters and super-enhancers through the BAF complex in embryonic stem cells
J Wang, X Wu, C Wei, X Huang, Q Ma, X Huang… - Stem cell reports, 2018 - cell.com
… in the OCT4-mediated pluripotency network in mouse embryonic stem cells (mESCs). The
interaction … Moreover, YY1 enriches at both promoter and super-enhancer regions to stimulate …
interaction … Moreover, YY1 enriches at both promoter and super-enhancer regions to stimulate …
[HTML][HTML] Super-enhancers in the control of cell identity and disease
D Hnisz, BJ Abraham, TI Lee, A Lau, V Saint-André… - Cell, 2013 - cell.com
… occupying super-enhancers in embryonic stem cells and … enhancers and super-enhancers
in ESCs. Similarly, it would be useful to know if super-enhancers are transcribed, as enhancer …
in ESCs. Similarly, it would be useful to know if super-enhancers are transcribed, as enhancer …
Super-enhancers conserved within placental mammals maintain stem cell pluripotency
J Zhang, Y Zhou, W Yue, Z Zhu, X Wu… - Proceedings of the …, 2022 - National Acad Sciences
… Emerging evidence suggests that groups of enhancers with … to form super-enhancers (SEs)
(10). Compared with typical … differentiation of mouse embryonic stem cells (ESCs) (61). The …
(10). Compared with typical … differentiation of mouse embryonic stem cells (ESCs) (61). The …
[HTML][HTML] Super-enhancers and CTCF in early embryonic cell fate decisions
P Agrawal, S Rao - Frontiers in cell and developmental biology, 2021 - frontiersin.org
… measure but reflect selected key studies in the field focusing on embryonic stem cells (ESCs).
For further information on enhancer and CTCF functions, we suggest these reviews (Ong …
For further information on enhancer and CTCF functions, we suggest these reviews (Ong …
Hippo-YAP signaling controls lineage differentiation of mouse embryonic stem cells through modulating the formation of super-enhancers
X Sun, Z Ren, Y Cun, C Zhao, X Huang… - Nucleic acids …, 2020 - academic.oup.com
… (H) ChIP-seq signal tracks of YAP and SE related factors at Enc1 distal enhancer in WT
ESCs. As we have found, YAP bound sites were enriched at acetylated enhancers and Sox2, …
ESCs. As we have found, YAP bound sites were enriched at acetylated enhancers and Sox2, …
[HTML][HTML] Super enhancer profiles identify key cell identity genes during differentiation from embryonic stem cells to trophoblast stem cells super enhencers in …
R Jia, Y Gao, S Guo, S Li, L Zhou, C Gou… - Frontiers in …, 2021 - frontiersin.org
… Embryonic stem cells (ESCs) are derived from the ICM, possess multipotential … Super
enhancers (SEs) are defined as clusters of enhancers consisting of abundant transcription factor …
enhancers (SEs) are defined as clusters of enhancers consisting of abundant transcription factor …