Zebrafish as a model to study the role of DNA methylation in environmental toxicology

JH Kamstra, P Aleström, JM Kooter, J Legler - Environmental Science and …, 2015 - Springer
… a model species in environmental epigenetics despite their … In this review, recent insights
in DNA methylation during … to study the role of DNA methylation in environmental toxicology. …

The implications of DNA methylation for toxicology: toward toxicomethylomics, the toxicology of DNA methylation

M Szyf - Toxicological Sciences, 2011 - academic.oup.com
role of DNA methylation has been programming gene expression through promoter/enhancer
methylation … on how we design assays for toxicity of agents that disrupt DNA methylation. …

Epigenetics and DNA methylation come of age in toxicology

RE Watson, JI Goodman - Toxicological sciences, 2002 - academic.oup.com
DNA methylation is also involved in imprinting, the phenomenon by which homologous …
that altered DNA methylation is not a mutation. In the current review, DNA methylation is the …

Environmental chemicals and DNA methylation in adults: a systematic review of the epidemiologic evidence

A Ruiz-Hernandez, CC Kuo, P Rentero-Garrido… - Clinical …, 2015 - Springer
… potential toxicity pathways specific to the environmental … between environmental chemicals
and DNA methylation levels, 10 … studies with multiple environmental toxicants evaluated in …

Role of DNA methylation in bisphenol A exposed mouse spermatocyte

L Yin, Y Dai, X Jiang, Y Liu, H Chen, F Han… - Environmental …, 2016 - Elsevier
… -wide DNA methylation level increased with increasing concentrations of BPA, which
suggested an important role for DNA methylation in GC-2 cell toxicity following BPA exposure. …

The impact of DNA methylation technologies on drug toxicology

A Dueñas-Gonzalez, B Alatorre… - … & toxicology, 2014 - Taylor & Francis
… of drug toxicology, as there are still many challenges to overcome before DNA methylation-…
Comprehensive whole-genome DNA methylation methods for a unbiased analysis based …

The role of DNA methylation in gene regulation

PA Bommarito, RC Fry - Toxicoepigenetics, 2019 - Elsevier
… the mechanisms for DNA demethylation, which plays an important role in embryonic … by
which DNA is methylated and demethylated, future clinical applications of DNA methylation in …

DNA methylation modifications: mediation to stipulate pesticide toxicity

D Mahna, S Puri, S Sharma - International Journal of Environmental …, 2021 - Springer
… indicates the involvement of DNA methylation alterations in pesticide mediated toxicity in
human, … and DNA methylation process. Table 1 Effect of various pesticides on DNA methylation

The role of epigenomics in aquatic toxicology

SM Brander, AD Biales… - Environmental toxicology …, 2017 - Wiley Online Library
… 3 major epigenetic mechanisms, DNA methylation, histone modification, and noncoding
RNAs (ncRNAs), are shared across most taxa, and that the response to environmental stressors, …

Metals exposures and DNA methylation: current evidence and future directions

ER Elkin, C Higgins, MT Aung, KM Bakulski - Current environmental health …, 2022 - Springer
… The other half of included toxicology studies evaluated genome-wide DNA methylation
with either whole genome bisulfite sequencing (WGBS), an expensive method that covers …