An evaluation of risk factors for adverse drug events associated with angiotensin‐converting enzyme inhibitors

T Morimoto, TK Gandhi, JM Fiskio… - Journal of evaluation …, 2004 - Wiley Online Library
… ACE inhibitors were discontinued because of adverse drug events. … drug events: age, female
gender, ethnicity other than African American or Latino, no history of previous ACE inhibitor

Targeting enzyme inhibitors in drug discovery

RA Copeland, MR Harpel… - Expert opinion on …, 2007 - Taylor & Francis
Drugs that function as enzyme inhibitors constitute a significant portion of the orally bioavailable
therapeutic agents that are in clinical use today. Likewise, much of drugevents in vivo. …

Adverse effects of the angiotensin-converting enzyme inhibitors

CP Alderman - Annals of Pharmacotherapy, 1996 - journals.sagepub.com
… patient monitoring are important when ACE inhibitor therapy is used for any indication.
Provided these steps are taken, ACE inhibitors are generally a safe and effective class of drugs. …

[图书][B] Evaluation of enzyme inhibitors in drug discovery: a guide for medicinal chemists and pharmacologists

RA Copeland - 2013 - books.google.com
… , Evaluation of Enzyme Inhibitors in Drug Discovery equips … of drugs that work by inhibiting
specific enzyme targets. … of enzyme inhibition and special treatments for enzymes that …

The ontogeny of drug metabolism enzymes and implications for adverse drug events

RN Hines - Pharmacology & therapeutics, 2008 - Elsevier
… Profound changes in drug metabolizing enzyme (DME) expression occurs during development
that impacts the risk of adverse drug events in the fetus and child. A review of our current …

[HTML][HTML] Effects of an angiotensin-converting–enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients

Heart Outcomes Prevention Evaluation … - … England Journal of …, 2000 - Mass Medical Soc
… Angiotensin-converting–enzyme inhibitors improve the outcome among patients with left …
enzyme inhibitor, ramipril, in patients who were at high risk for cardiovascular events but …

Enzyme inhibitors in medicine

CSJ Walpole, R Wrigglesworth - Natural Product Reports, 1989 - pubs.rsc.org
… , diseases, enzyme inhibitors, and their attendant clinical benefits. This … enzyme inhibitors.
Accordingly, this review is structured towards this end, with an emphasis on molecular events

Are all angiotensin-converting enzyme inhibitors interchangeable?

CD Furberg, B Pitt - Journal of the American College of Cardiology, 2001 - jacc.org
… or prevention of ischemic events. A prudent action is the assumption that the benefits of a
particular ACE inhibitor apply primarily to the investigated indication, doses and outcomes. …

Overview of the angiotensin-converting-enzyme inhibitors

RW Piepho - American journal of health-system pharmacy, 2000 - academic.oup.com
… of ACE inhibitors. ACE has a … enzyme (ACE) inhibitors and their role in the renin–angiotensin
system (RAS) are described, and pharmacokinetic properties and common adverse events

[HTML][HTML] Pattern of Angiotensin-converting enzyme inhibitors induced adverse drug reactions in South Indian teaching hospital

UV Mateti, H Nekkanti, R Vilakkathala… - … American journal of …, 2012 - ncbi.nlm.nih.gov
… of ADRs due to angiotensin-converting enzyme Inhibitors in cardiology department. … -risk
patients suffering from cardiovascular events. ACE inhibitors have specific effect on myocardial …