Reprogramming DNA methylation in the mammalian life cycle: building and breaking epigenetic barriers
… DNA methylation reprogramming in the mammalian life cycle. DNA methylation marks
represent an epigenetic barrier in mammalian development that is demolished when …
represent an epigenetic barrier in mammalian development that is demolished when …
DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos
DM Messerschmidt, BB Knowles… - Genes & …, 2014 - genesdev.cshlp.org
… Methylation of DNA is an essential epigenetic control … , and DNA methylation poses a
fundamental epigenetic barrier that guides … DNA methylation also plays an important role in sex …
fundamental epigenetic barrier that guides … DNA methylation also plays an important role in sex …
New insights into mechanisms that regulate DNA methylation patterning
G Ficz - Journal of Experimental Biology, 2015 - journals.biologists.com
… establishes epigenetic barriers to avoid transition from one state to another. Epigenetic barriers
are … can constitute a roadblock or epigenetic barrier. In mammalian development, the first …
are … can constitute a roadblock or epigenetic barrier. In mammalian development, the first …
Stepwise DNA methylation changes are linked to escape from defined proliferation barriers and mammary epithelial cell immortalization
… changes identified in this study can potentially provide a bank of epigenetic biomarkers
for assessing breast cancer risk and allow for the analysis of multiple post-stasis and …
for assessing breast cancer risk and allow for the analysis of multiple post-stasis and …
DNA methylation patterns and epigenetic memory
A Bird - Genes & development, 2002 - genesdev.cshlp.org
… or exclude methylation support the idea that DNA methylation is … Barriers to spreading
would lead to the formation of CpG islands. A hypothetical trigger for DNA methylation is DNA …
would lead to the formation of CpG islands. A hypothetical trigger for DNA methylation is DNA …
Epigenetic regulation in pluripotent stem cells: a key to breaking the epigenetic barrier
A Watanabe, Y Yamada… - … Transactions of the …, 2013 - royalsocietypublishing.org
… an epigenetic barrier, and these cells acquire pluripotency by breaking the epigenetic barrier
by … how such differential levels of DNA methylation arise, functional linkage between DNA …
by … how such differential levels of DNA methylation arise, functional linkage between DNA …
Epigenetics and stroke: role of DNA methylation and effect of aging on blood–brain barrier recovery
CM Phillips, SM Stamatovic, RF Keep… - … and Barriers of the CNS, 2023 - Springer
… epigenetic factors play a significant role in regulating post-stroke BBB recovery. This study
aimed to evaluate the epigenetic … DNA methylation profiling of poststroke brain microvessels …
aimed to evaluate the epigenetic … DNA methylation profiling of poststroke brain microvessels …
Epigenetic interplay between histone modifications and DNA methylation in gene silencing
T Vaissière, C Sawan, Z Herceg - Mutation Research/Reviews in Mutation …, 2008 - Elsevier
… what is the hierarchical order of epigenetic events during unscheduled gene silencing in …
how DNA methylation and histone acetylation communicate to keep the histone–DNA complex …
how DNA methylation and histone acetylation communicate to keep the histone–DNA complex …
DNA methylation: an epigenetic mark of cellular memory
M Kim, J Costello - Experimental & molecular medicine, 2017 - nature.com
… This review covers DNA methylation as a form of epigenetic … barriers to reprogramming,
including p53 and Ink4A/Arf, function as tumor suppressors. DNA methylation is a potent barrier …
including p53 and Ink4A/Arf, function as tumor suppressors. DNA methylation is a potent barrier …
DNA methylation and the preservation of cell identity
O Bogdanović, R Lister - Current opinion in genetics & development, 2017 - Elsevier
… This work provides an example of how locus-specific mC can serve as an epigenetic barrier
that prevents premature transitions in cell identity. Altogether, it appears that mC, at least in …
that prevents premature transitions in cell identity. Altogether, it appears that mC, at least in …
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