A multistep epigenetic switch enables the stable inheritance of DNA methylation states
HN Lim, A Van Oudenaarden - Nature genetics, 2007 - nature.com
… The other partial state occurs when there is a 'naked' switch region without DNA methylation
… OxyR binding does, however, block DNA methylation. As a result, the U O partial expression …
… OxyR binding does, however, block DNA methylation. As a result, the U O partial expression …
Metaboloepigenetics: interrelationships between energy metabolism and epigenetic control of gene expression
DR Donohoe, SJ Bultman - Journal of cellular physiology, 2012 - Wiley Online Library
… the role of epigenetics as a mechanistic link between energy metabolism and control of gene
… Mechanistically, epigenetics involves changes in either DNA methylation [which occurs …
… Mechanistically, epigenetics involves changes in either DNA methylation [which occurs …
A concerted DNA methylation/histone methylation switch regulates rRNA gene dosage control and nucleolar dominance
… Here, we present evidence for an epigenetic switch in which concerted changes in promoter
… We next tested whether or not promoter DNA methylation was tightly correlated with H3K9 …
… We next tested whether or not promoter DNA methylation was tightly correlated with H3K9 …
Genomic patterns of DNA methylation: targets and function of an epigenetic mark
M Weber, D Schübeler - Current opinion in cell biology, 2007 - Elsevier
… DNA methylation on a genome-wide scale have given new insights into the biological function
of DNA methylation … we will not focus on aberrant DNA methylation in cancer, for which we …
of DNA methylation … we will not focus on aberrant DNA methylation in cancer, for which we …
[HTML][HTML] Epigenetic regulation of myofibroblast differentiation by DNA methylation
B Hu, M Gharaee-Kermani, Z Wu, SH Phan - The American journal of …, 2010 - Elsevier
… DNA methylation, a key mechanism of repressing gene expression, is of particular … We
analyzed the extent and regulation of DNA methylation of the α-smooth muscle actin (α-SMA) …
analyzed the extent and regulation of DNA methylation of the α-smooth muscle actin (α-SMA) …
Genomic imprinting–a model for roles of histone modifications in epigenetic control
KR McEwen, AC Ferguson-Smith - Epigenomics, 2009 - Springer
… acquisition of DNA methylation at CG … epigenetic control of gene activity and repression in
mammals, and the functional relationship between histone modifications and DNA methylation …
mammals, and the functional relationship between histone modifications and DNA methylation …
Epigenetic interplay between histone modifications and DNA methylation in gene silencing
T Vaissière, C Sawan, Z Herceg - Mutation Research/Reviews in Mutation …, 2008 - Elsevier
… Evidence suggests that these marks are dynamically linked in the epigenetic control of
gene expression and that their deregulation plays an important role in tumourigenesis [1], [6]. …
gene expression and that their deregulation plays an important role in tumourigenesis [1], [6]. …
Epigenetic control of hypertension by DNA methylation: a real possibility
PM João Job, FA dos Reis Lívero… - Current Pharmaceutical …, 2021 - ingentaconnect.com
… advances in research on DNA methylation in the development of … Studies of the involvement
of DNA methylation have greatly … recent findings of DNA methylation in hypertension, mainly …
of DNA methylation have greatly … recent findings of DNA methylation in hypertension, mainly …
Targeting deregulated epigenetic control in cancer
SK Zaidi, AJ Van Wijnen, JB Lian… - Journal of cellular …, 2013 - Wiley Online Library
… —especially the reversible silencing of genes—is critical for key biological processes,
targeting DNA methylation machinery inevitably results in unintended consequences, often …
targeting DNA methylation machinery inevitably results in unintended consequences, often …
Stress, epigenetic control of gene expression and memory formation
AF Trollope, M Gutièrrez-Mecinas, KR Mifsud… - Experimental …, 2012 - Elsevier
… DNA methylation and its role in epigenetics Another major epigenetic process is DNA
methylation, which involves the covalent addition of a methyl group to the 5-position of the …
methylation, which involves the covalent addition of a methyl group to the 5-position of the …