DNA methylation profiling in the clinic: applications and challenges
H Heyn, M Esteller - Nature Reviews Genetics, 2012 - nature.com
… This Review focuses on epigenetic profiling at the level of DNA methylation 7,8 . There is
an emphasis on neoplasia, as this is the area in which using these epigenetic markers is best …
an emphasis on neoplasia, as this is the area in which using these epigenetic markers is best …
DNA methylation profiles in cancer diagnosis and therapeutics
Y Pan, G Liu, F Zhou, B Su, Y Li - Clinical and experimental medicine, 2018 - Springer
… Epigenetics does not cause mutation in DNA sequence, but are causal interactions …
DNA methylation is considered as one epigenetic mechanism [3]. Epigenetic changes could …
DNA methylation is considered as one epigenetic mechanism [3]. Epigenetic changes could …
Comprehensive DNA methylation profiling in a human cancer genome identifies novel epigenetic targets
JM Ordway, JA Bedell, RW Citek, A Nunberg… - …, 2006 - academic.oup.com
… driving carcinogenesis from the epigenetic perspective, as well … microarray-based DNA
methylation profiling approach for use … epigenetic alteration in disease, but also as an epigenetic ‘…
methylation profiling approach for use … epigenetic alteration in disease, but also as an epigenetic ‘…
DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients
M Volkmar, S Dedeurwaerder, DA Cunha… - The EMBO …, 2012 - embopress.org
… In this study, we performed the first comprehensive DNA methylation profiling in pancreatic
… significant differential DNA methylation in diabetic islets. These methylation changes were …
… significant differential DNA methylation in diabetic islets. These methylation changes were …
DNA methylation profiling identifies epigenetic differences between diabetes patients with ESRD and diabetes patients without nephropathy
C Sapienza, J Lee, J Powell, O Erinle, F Yafai… - Epigenetics, 2011 - Taylor & Francis
… or transcription profiling studies suggests strongly that the DNA methylation differences we
observe … in DNA extracted from saliva offers proof-of-principle that inter-individual epigenetic …
observe … in DNA extracted from saliva offers proof-of-principle that inter-individual epigenetic …
Forensic DNA methylation profiling—potential opportunities and challenges
A Vidaki, B Daniel, DS Court - Forensic Science International: Genetics, 2013 - Elsevier
… As mentioned earlier, DNA methylation is an epigenetic mechanism that changes gene
expression. Recent studies have demonstrated that various diseases and cancer are associated …
expression. Recent studies have demonstrated that various diseases and cancer are associated …
Genome wide DNA methylation profiling for epigenetic alteration in coronary artery disease patients
… -wide methylation profiling using CpG island array and identified differentially methylated …
work relates to the possibility that DNA sequence variations can confound DNA methylation …
work relates to the possibility that DNA sequence variations can confound DNA methylation …
DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker
… epigenetic biomarker in blood. Consequently, we performed DNA methylation profiling using
DNA … breast cancer and the Infinium DNA methylation BeadChip technology covering more …
DNA … breast cancer and the Infinium DNA methylation BeadChip technology covering more …
Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19
MJ Corley, APS Pang, K Dody, PA Mudd… - Journal of leukocyte …, 2021 - academic.oup.com
… hijacking the epigenetic landscape of … epigenetic changes associated with severe SARS-CoV-2
infection pathology. Here, we examined genome-wide DNA methylation (DNAm) profiles …
infection pathology. Here, we examined genome-wide DNA methylation (DNAm) profiles …
[HTML][HTML] Genome-wide DNA methylation profiling reveals novel epigenetic signatures in squamous cell lung cancer
YX Shi, Y Wang, X Li, W Zhang, HH Zhou, JY Yin… - BMC genomics, 2017 - Springer
… Here we performed DNA methylation profiling on 24 LUSC and paired non-tumor lung (NTL…
Human Methylation 450 K BeadArrays, and identified 5214 differentially methylated probes. …
Human Methylation 450 K BeadArrays, and identified 5214 differentially methylated probes. …
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