DNA methylation profiling in the clinic: applications and challenges

H Heyn, M Esteller - Nature Reviews Genetics, 2012 - nature.com
… This Review focuses on epigenetic profiling at the level of DNA methylation 7,8 . There is
an emphasis on neoplasia, as this is the area in which using these epigenetic markers is best …

DNA methylation profiles in cancer diagnosis and therapeutics

Y Pan, G Liu, F Zhou, B Su, Y Li - Clinical and experimental medicine, 2018 - Springer
Epigenetics does not cause mutation in DNA sequence, but are causal interactions …
DNA methylation is considered as one epigenetic mechanism [3]. Epigenetic changes could …

Comprehensive DNA methylation profiling in a human cancer genome identifies novel epigenetic targets

JM Ordway, JA Bedell, RW Citek, A Nunberg… - …, 2006 - academic.oup.com
… driving carcinogenesis from the epigenetic perspective, as well … microarray-based DNA
methylation profiling approach for use … epigenetic alteration in disease, but also as an epigenetic ‘…

DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients

M Volkmar, S Dedeurwaerder, DA Cunha… - The EMBO …, 2012 - embopress.org
… In this study, we performed the first comprehensive DNA methylation profiling in pancreatic
… significant differential DNA methylation in diabetic islets. These methylation changes were …

DNA methylation profiling identifies epigenetic differences between diabetes patients with ESRD and diabetes patients without nephropathy

C Sapienza, J Lee, J Powell, O Erinle, F Yafai… - Epigenetics, 2011 - Taylor & Francis
… or transcription profiling studies suggests strongly that the DNA methylation differences we
observe … in DNA extracted from saliva offers proof-of-principle that inter-individual epigenetic

Forensic DNA methylation profiling—potential opportunities and challenges

A Vidaki, B Daniel, DS Court - Forensic Science International: Genetics, 2013 - Elsevier
… As mentioned earlier, DNA methylation is an epigenetic mechanism that changes gene
expression. Recent studies have demonstrated that various diseases and cancer are associated …

Genome wide DNA methylation profiling for epigenetic alteration in coronary artery disease patients

P Sharma, G Garg, A Kumar, F Mohammad, SR Kumar… - Gene, 2014 - Elsevier
… -wide methylation profiling using CpG island array and identified differentially methylated
work relates to the possibility that DNA sequence variations can confound DNA methylation

DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker

H Heyn, FJ Carmona, A Gomez, HJ Ferreira… - …, 2013 - academic.oup.com
epigenetic biomarker in blood. Consequently, we performed DNA methylation profiling using
DNA … breast cancer and the Infinium DNA methylation BeadChip technology covering more …

Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19

MJ Corley, APS Pang, K Dody, PA Mudd… - Journal of leukocyte …, 2021 - academic.oup.com
… hijacking the epigenetic landscape of … epigenetic changes associated with severe SARS-CoV-2
infection pathology. Here, we examined genome-wide DNA methylation (DNAm) profiles

[HTML][HTML] Genome-wide DNA methylation profiling reveals novel epigenetic signatures in squamous cell lung cancer

YX Shi, Y Wang, X Li, W Zhang, HH Zhou, JY Yin… - BMC genomics, 2017 - Springer
… Here we performed DNA methylation profiling on 24 LUSC and paired non-tumor lung (NTL…
Human Methylation 450 K BeadArrays, and identified 5214 differentially methylated probes. …