Distinguishing epigenetic marks of developmental and imprinting regulation
KR McEwen, AC Ferguson-Smith - Epigenetics & chromatin, 2010 - Springer
… We have used imprinted genes as a model system to compare epigenetic … have a significantly
different epigenetic profile for these four marks to imprinted genes without a promoter DMR …
different epigenetic profile for these four marks to imprinted genes without a promoter DMR …
Genomic imprinting: employing and avoiding epigenetic processes
MS Bartolomei - Genes & development, 2009 - genesdev.cshlp.org
… Genomic imprinting refers to an epigenetic mark that … more on epigenetic mechanisms while
at the same time evading them. The alleles of imprinted genes are marked epigenetically at …
at the same time evading them. The alleles of imprinted genes are marked epigenetically at …
Imprinting and epigenetic changes in the early embryo
JR Weaver, M Susiarjo, MS Bartolomei - Mammalian Genome, 2009 - Springer
… DNA methylation is the best-established epigenetic mark that is critical for the allele-specific
expression of imprinted genes. This mark must be correctly established in the germline, …
expression of imprinted genes. This mark must be correctly established in the germline, …
Genomic imprinting: the emergence of an epigenetic paradigm
AC Ferguson-Smith - Nature Reviews Genetics, 2011 - nature.com
… -wide epigenetic marks is deciphering which marks are instructive, which marks are occurring
as … of transcription or repression) and which marks are less relevant than others. Applying …
as … of transcription or repression) and which marks are less relevant than others. Applying …
Genomic imprinting: intricacies of epigenetic regulation in clusters
RI Verona, MRW Mann… - Annual review of cell and …, 2003 - annualreviews.org
… However, the exact nature of the epigenetic mark remainsto be established. Generally, it
is accepted that imprinted genes possess acis-acting regulatory sequence that controls the …
is accepted that imprinted genes possess acis-acting regulatory sequence that controls the …
[HTML][HTML] Epigenetic control of the genome—lessons from genomic imprinting
BT Adalsteinsson, AC Ferguson-Smith - Genes, 2014 - mdpi.com
… Great effort has recently been undertaken to catalogue the genome-wide patterns of epigenetic
marks—creating reference epigenomes—which will deepen our understanding of their …
marks—creating reference epigenomes—which will deepen our understanding of their …
[HTML][HTML] Basic concepts of epigenetics
M Inbar-Feigenberg, S Choufani, DT Butcher… - Fertility and sterility, 2013 - Elsevier
… imprinting; they regulate gene expression in a dosage-dependent and parent-of-origin-specific
manner, respectively. Both genetic and environmental factors impact epigenetic marks, …
manner, respectively. Both genetic and environmental factors impact epigenetic marks, …
Epigenetic mechanisms underlying genomic imprinting in plants
… In terms of epigenetic mechanisms, imprinted expression is … of imprinted genes, whereby
the position of such epigenetic … as an important epigenetic mark distinguishing maternally …
the position of such epigenetic … as an important epigenetic mark distinguishing maternally …
Imprinting and looping: epigenetic marks control interactions between regulatory elements
… influence gene expression and how epigenetic modifications … H19 genes are located in the
distal part of chromosome 7 with a 90-kb interval. These two genes are reciprocally imprinted …
distal part of chromosome 7 with a 90-kb interval. These two genes are reciprocally imprinted …
Methylation of DNA—one of the major epigenetic markers
SV Salozhin, EB Prokhorchuk, GP Georgiev - Biochemistry (Moscow), 2005 - Springer
… These CpG islands belong to imprinted genes or genes on inac tivated X chromosome.
Promotors associated with such CpG islands remain silent during the whole life of the organism. …
Promotors associated with such CpG islands remain silent during the whole life of the organism. …
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