… (CIMPs), defined as DNA hypermethylation at specific CpG … This review details the DNA
methylation alterations in CRC, … application of epigenetic therapies for CRC patient treatment. …

… capable of altering epigenetic states, including DNA methylation patterns and … epigenetic
drugs based on the inhibition of DNA methylation. Combinatorial therapies that couple DNA …

… This review will focus on epigenetic therapy, and the use of drugs to correct epigenetic …
Inhibition of DNA methylation can be therapeutically useful in cancer where hypermethylation of …

… and directed by the epigenetic signature, which, in … DNA methylation and histone post-translational
modifications in atherosclerosis. The future research directions and potential therapy …

… 11,12,13 , and this has also been shown in mammals, where H3-K9 methylation directs
DNA methylation to pericentromeric heterochromatin 14 . Interactions between histone …

… includes combining different epigenetic therapies (DNA methylation and histone acetylation
… ), and attempting to integrate epigenetic therapy with more standard therapy. Two trials have …

… (a) DNA methylation and histone modification status vary across different genomic contexts
and collectively regulate gene expression. The best understood histone modifications …

… DNA methylation is the most characterized epigenetic phenomenon described as a stable
epigenetic … to distinguish the effect of the epigenetic therapy from the cytotoxic therapy (17). On …

… cancer-specific epigenetic changes are alterations in DNA methylation and histone acetylation…
hypermethylation and chromatin events that are closely tied to DNA methylation changes. …

… of epigenetic therapy involving the use of DNA methylation … Here we will focus on DNA
methylation inhibitors and … of DNA methylation and study its potential use as an epigenetic …