… question the conservation of transposon methylation (9). To understand how eukaryotic
DNA methylation has evolved, we quantified DNA methylation by deep bisulfite sequencing in …

… to eukaryotic DNA methylation, we have focused on its distribution both between and within
organisms, on the diversity of Mtases, and on the variety of functions in which methylation is …

… across eukaryotes.8, 17 In this chapter, we primarily focus on DNA methylation, with an
emphasis on cytosine methylation and its further modification in eukaryotes and their viruses. …

… Their data allowed a comprehensive comparison of whole-genome methylation profiles …
divergent features of DNA methylation in eukaryotes. Although DNA methylation appears to be a …

… The introduction of artificially methylated DNA sequences into individual eukaryotic cells by
… In the meantime, the study of eukaryotic DNA methylation promises to contribute much to …

… of de novo patterns of DNA methylatton is characterized … of DNA methylation by an essentially
unknown mechanism. In this review, some of the general concepts of DNA methylation in …

The occurrence of methylated cytosine or adenine in cellular DNA appears to be almost
universal. In prokaryotes both N6-methyladenine (meA) and 5-methylcytosine (mSC) have been …

… DNA methylation, particularly in eukaryotic systems. In 1975, several groups of researchers
… a role for DNA methylation in the regulation of gene expression in eukaryotes (Riggs, 1975; …

… of DNA methylation across eukaryotic organisms. I will attempt to show how we are starting
to move beyond a characterisation of the evolution of DNA methylation … of DNA methylation …

… enzymes whose action is blocked by DNA methylation. Such enzymes can be used to
ask whether or not their recognition site is methylated in eukaryotic DNA. The use of such …