DNA methylation and gene expression
Z Siegfried, I Simon - Wiley Interdisciplinary Reviews: Systems …, 2010 - Wiley Online Library
… The third and smallest group (7%) represents CGI promoters that are DNA methylated (filled
circles). There is no clear correlation between this group and any specific chromatin marks (…
circles). There is no clear correlation between this group and any specific chromatin marks (…
Expression of various genes is controlled by DNA methylation during mammalian development
M Ehrlich - Journal of cellular biochemistry, 2003 - Wiley Online Library
… on expression are not due to vector methylation. Lastly, while experiments involving inhibition
of DNA methylation … of changes in methylation of a given promoter on the expression of the …
of DNA methylation … of changes in methylation of a given promoter on the expression of the …
Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer
… promoter DNA methylation in cancer is to understand how this DNA modification actually
modulates gene expression. … Through such complexes, sites of DNA methylation could then …
modulates gene expression. … Through such complexes, sites of DNA methylation could then …
Targets and dynamics of promoter DNA methylation during early mouse development
J Borgel, S Guibert, Y Li, H Chiba, D Schübeler… - Nature …, 2010 - nature.com
… To further assess the function of promoter DNA methylation, we measured the expression
of several target genes by RT-qPCR in wildtype and mutant E9.5 embryos. Although all genes …
of several target genes by RT-qPCR in wildtype and mutant E9.5 embryos. Although all genes …
Insulin gene expression is regulated by DNA methylation
… gene expression been investigated, and in this study we examine the role of DNA methylation
… and that the insulin gene promoter is specifically demethylated in insulin-producing cells. …
… and that the insulin gene promoter is specifically demethylated in insulin-producing cells. …
Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA1c levels in human pancreatic islets
BT Yang, TA Dayeh, CL Kirkpatrick, J Taneera… - Diabetologia, 2011 - Springer
… for 72 h increased insulin promoter DNA methylation in clonal rat beta cells. Although we
cannot rule out that the changes we find in insulin promoter DNA methylation in type 2 diabetic …
cannot rule out that the changes we find in insulin promoter DNA methylation in type 2 diabetic …
Cyclical DNA methylation of a transcriptionally active promoter
R Métivier, R Gallais, C Tiffoche, C Le Péron… - Nature, 2008 - nature.com
… This is sufficient to observe an induction of pS2 gene expression, and to generate a cell
population in which we can observe all proteins that are present on E 2 -activated pS2 …
population in which we can observe all proteins that are present on E 2 -activated pS2 …
DNA methylation profile of tissue-dependent and differentially methylated regions (T-DMRs) in mouse promoter regions demonstrating tissue-specific gene expression
S Yagi, K Hirabayashi, S Sato, W Li… - Genome …, 2008 - genome.cshlp.org
… the extent of DNA methylation in the regulation of gene expression in the mammalian … -wide
DNA methylation analysis method for tissue-dependent and differentially methylated …
DNA methylation analysis method for tissue-dependent and differentially methylated …
DNA methylation
R Singal, GD Ginder - Blood, The Journal of the American …, 1999 - ashpublications.org
… have shown the ability of promoter DNA methylation to inhibit … could induce similar increases
in γ-globin gene expression,… gene expression through the use of global DNA methylation …
in γ-globin gene expression,… gene expression through the use of global DNA methylation …
DNA methylation in glioblastoma: impact on gene expression and clinical outcome
… Changes in promoter DNA methylation pattern of genes … technology for quantitative expression
and methylation profiling in a … between DNA methylation pattern and gene expression in …
and methylation profiling in a … between DNA methylation pattern and gene expression in …
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