… human renal diseases, concentrates on the regulation of apoptosis by extracellular matrix
(ECM), and considers how this type of cell death might be involved in diabetic renal disease …

… The aim of this review is to give an insight of the involvement of the extracellular matrix (ECM)
proteins in kidney diseases and as a source of potential novel biomarkers of renal fibrosis. …

… A study using a cell-type specific knock-out of collagen type I provided first evidence for
direct functional involvement of collagen in kidney diseases. The effects were dependent on …

… key mechanism in the development of glomerular disease, as exemplified by the … kidney
disease. This Review summarizes the role of heparanase in the development of kidney disease…

… They were previously thought to be anti-fibrotic because of their ability to degrade and
remodel of extracellular matrix. However, recent studies have shown that MMPs are implicated in …

… from the nephrons and collecting ducts of affected kidneys. Cysts are thought to initiate as
… of pronounced extracellular matrix changes have been found in the cystic kidneys of several …

… little is known about the distribution and function of these molecules in renal disease. In
the context of kidney disease, attention has focused primarily on the role of integrins in acute …

Extracellular matrix (ECM) components, commonly thought to function purely as structural
elements are now demonstrated to act as signaling molecules. With the identification of matrix-…

… In studies using single matrix components, the strongest proliferative response was seen …
and extracellular matrix production by ADPKD cells Adult human polycystic kidney disease (…

… of diabetic renal disease once it has developed by regulating extracellular matrix, TGF-β, and
… this renoprotection is by regulating extracellular matrix (ECM) protein expression (26, 27). …