… and technology development related to extracellular vesicles (EVs). Secretion of EVs is a
fundamental and evolutionarily conserved biological process broadly found from bacteria to …

… Extracellular vesicles (EVs) exert their biological functions by delivering proteins, metabolites,
and nucleic acids to recipient cells. EVs play important roles in cancer development. The …

… and cancer cells, the differences in their content, surface characteristics, timing of release,
and other parameters of EV biology, will have important implications for cancer biology and …

… physiological and functional roles in cancer biology. The goal of this review is to critically
evaluate the evidence of a role for EVs in cancer biology from a biochemical perspective. We …

… These particles are known as extracellular vesicles (EVs) and include species of exosomes
and shed microvesicles. EVs carry molecules such as oncoproteins and oncopeptides, RNA …

… Moreover, both unmodified and engineered extracellular vesicles are likely to have … in
understanding extracellular vesicle biology and the role of extracellular vesicles in disease, …

… Citation65 Further, functional studies have identified cancer-associated fibroblast-derived
extracellular vesicles containing whole genomic mitochondrial DNA in patients and xenograft …

… Of particular interest are distant and systemic effects of EVs in cancer biology. Cancer-derived
exosomes have been implicated as immunomodulators 24, 43, 59, 72-74. Circulating EVs …

Extracellular vesicles (EVs) are a heterogeneous group of structures which can be classified
into smaller in size and relatively homogenous exosomes (EXSMs)—spherical fragments of …

… both the intrinsic cell “state” and the extracellular signals cells received from their environment.
… cell biological processes that couple exosome biogenesis to cargo sorting in cancer cells. …