Signaling by extracellular vesicles advances cancer hallmarks

M Kanada, MH Bachmann, CH Contag - Trends in cancer, 2016 - cell.com
… Mammalian cells secrete various extracellular vesicles (EVs; … Each vesicle type can
originate from normal or cancerous … and maintenance of cancer hallmarks, including sustaining …

The role of extracellular vesicles in the hallmarks of cancer and drug resistance

CPR Xavier, HR Caires, MAG Barbosa, R Bergantim… - Cells, 2020 - mdpi.com
… the role of EVs in affecting cancer hallmark traits by: (i) promoting cell proliferation and
escape from apoptosis, (ii) sustaining angiogenesis, (iii) contributing to cancer cell invasion and …

Adipose tissue-derived extracellular vesicles and the tumor microenvironment: revisiting the hallmarks of cancer

JA Moraes, C Encarnação, VA Franco… - Cancers, 2021 - mdpi.com
… We provide evidence to support that extracellular vesicles secreted by adipose tissues may
… functions of cancer cells, as described in the seminal report “The Hallmarks of Cancer” by …

Small extracellular vesicles (exosomes) and their cargo in pancreatic cancer: Key roles in the hallmarks of cancer

LM Channon, VM Tyma, Z Xu, DW Greening… - … )-Reviews on Cancer, 2022 - Elsevier
… Recently, small/nanosized extracellular vesicles (sEVs), including exosomes, have gained
… due to their emerging roles in cancer progression and diagnosis. Extracellular vesicles (EVs) …

Extra-cellular vesicles carry proteome of cancer hallmarks

AS Carvalho, H Baeta, BC Silva, MCS Moraes… - Frontiers in …, 2020 - hal.science
… Therefore, we apply the term ‘EV’ to include all types of extracellular vesicles to prevent
flawed interpretation of the data. Previous studies mostly define EVs functional role as: 1) ways …

The contribution of tumour-derived exosomes to the hallmarks of cancer

K Meehan, LJ Vella - Critical reviews in clinical laboratory sciences, 2016 - Taylor & Francis
… In this review, the term exosome refers to small (30–150 nm) extracellular vesicles, regardless
… exosomes (small extracellular vesicles of endosomal origin) were isolated in all instances. …

The extracellular matrix modulates the hallmarks of cancer

MW Pickup, JK Mouw, VM Weaver - EMBO reports, 2014 - embopress.org
extracellular matrix influence each of these cancer hallmarks and … We suggest that the success
of cancer prevention and … the evolving extracellular matrix, the tumor cells and its cancer‐…

Extracellular vesicles and epigenetic modifications are hallmarks of melanoma progression

F Mannavola, S D'Oronzo, M Cives, LS Stucci… - International Journal of …, 2019 - mdpi.com
vesicles have not yet been demonstrated in melanoma, the release of these large vesicles
… , which suggests that oncosomes may be a hallmark of cancer cells [13]. Proteins enriched in …

Phenotypic and proteomic analysis identifies hallmarks of blood circulating extracellular vesicles in NSCLC responders to immune checkpoint inhibitors

D Brocco, P Lanuti, D Pieragostino, MC Cufaro… - Cancers, 2021 - mdpi.com
… -derived extracellular vesicles (EV) in … extracellular vesicle concentration and
immunotherapy-related clinical outcomes. We also observed differences in circulating extracellular

How cancer cells dictate their microenvironment: present roles of extracellular vesicles

Y Naito, Y Yoshioka, Y Yamamoto, T Ochiya - Cellular and Molecular Life …, 2017 - Springer
cancer cells interact with each other and form the intrinsic communication networks that affect
several cancer hallmarks, … advances in cancer biology revealed that extracellular vesicles (…