Monitoring therapy efficiency in cancer through extracellular vesicles

I Stevic, G Buescher, FL Ricklefs - Cells, 2020 - mdpi.com
… patients and real-time monitoring of treatment response. Recently, … therapeutic applications.
In this review, we discuss the potential of EVs in monitoring the efficacy of cancer therapies

Extracellular vesicles and their potential use in monitoring cancer progression and therapy: the contribution of proteomics

MC Cufaro, D Pieragostino, P Lanuti… - Journal of …, 2019 - Wiley Online Library
… In conclusion, cell-derived membrane vesicles seem to separate and protect their contents
from extracellular environment allowing their cargoes to be transported intact and to form a …

Multiplexed profiling of biomarkers in extracellular vesicles for cancer diagnosis and therapy monitoring

S Zhou, Y Yang, Y Wu, S Liu - Analytica chimica acta, 2021 - Elsevier
Extracellular vesicles (EVs) are nanoscale vesicles secreted … diagnosis and treatment
response monitoring. However, the … accurate cancer diagnosis, therapy monitoring, and cancer …

Protein analysis of extracellular vesicles to monitor and predict therapeutic response in metastatic breast cancer

F Tian, S Zhang, C Liu, Z Han, Y Liu, J Deng… - Nature …, 2021 - nature.com
extracellular vesicles (EVs) provides a promising noninvasive means to diagnose, monitor,
and … For MBC patients undergoing therapies, the EV signature can accurately monitor the …

Extracellular vesicle drug occupancy enables real-time monitoring of targeted cancer therapy

S Pan, Y Zhang, A Natalia, CZJ Lim, NRY Ho… - Nature …, 2021 - nature.com
monitoring. Here we develop an analytical platform that leverages circulating extracellular
vesicles (… The technology, termed extracellular vesicle monitoring of small-molecule chemical …

Circulating extracellular vesicles are effective biomarkers for predicting response to cancer therapy

E Zhou, Y Li, F Wu, M Guo, J Xu, S Wang, Q Tan… - …, 2021 - thelancet.com
… In this review, we summarize the potential clinical significance of EVs and their cargos in
therapeutic response monitoring and prediction in several cancers (mainly lung cancer, …

Tracking extracellular vesicle phenotypic changes enables treatment monitoring in melanoma

J Wang, A Wuethrich, AAI Sina, RE Lane, LL Lin… - Science …, 2020 - science.org
… to track therapy … , extracellular vesicles (EVs) have emerged as informative biomarkers with
high potential to become an important tool for cancer diagnosis and therapy monitoring (3, 4). …

[HTML][HTML] Multiplexed electrokinetic sensor for detection and therapy monitoring of extracellular vesicles from liquid biopsies of non-small-cell lung cancer patients

S Cavallaro, P Hååg, SS Sahu, L Berisha… - Biosensors and …, 2021 - Elsevier
… Liquid biopsies based on extracellular vesicles (EVs) represent a promising tool for treatment
monitoring of tumors, including non-small-cell lung cancers (NSCLC). In this study, we …

Nanoplasmonic quantification of tumour-derived extracellular vesicles in plasma microsamples for diagnosis and treatment monitoring

K Liang, F Liu, J Fan, D Sun, C Liu, CJ Lyon… - Nature biomedical …, 2017 - nature.com
… Circulating CA19-9 levels are sometimes used to monitor treatment … therapy regimens.
Our results suggest that an nPES EphA2-EV blood assay can be used to monitor therapy

Extracellular vesicles as a novel source of biomarkers in liquid biopsies for monitoring cancer progression and drug resistance

MH Vasconcelos, HR Caires, A Ābols… - Drug Resistance …, 2019 - Elsevier
Cancer-derived extracellular vesicles (EVs) have been detected in the bloodstream and other
biofluids of cancer patients. They carry various tumor-derived molecules such as mutated …