… Moreover, cerebral blood flow response to the hypercapnic-hypoxia challenge (in terms of
% … hypercapnic-hypoxia gas challenge may be a useful maneuver in physiological MRI as it …

… meal challenge, but only four completed the gas challenge. … the gas challenge was low
compared with the meal challenge, … feasibility of performing a gas challenge in a clinical setting. …

… and cessation of a gas challenge allows repeated measurements during MRI (unlike …
has therefore been used to: demonstrate physiological impairments such as reduced vascular …

… while the subject is lying inside the MRI scanner. Using this … Physiological parameters and
MRI images were recorded … room-air and hypercapnic gas breathing. Representative results …

… In order to allow for physiological stabilization, especially after the change of breathing …
the oxygen-sensitive MRI response of tumors to hypoxic gas breathing challenge. BOLD and …

… in MRI-compatible gas delivery apparatus. In this review, we first discuss the physiological
basis of … We then review the methodological aspects of CVR mapping, including gas delivery …

… without the need for external gas challenges have been proposed. … Despite the multitude
of alternatives to gas challenges, … based on MRI and CO 2 variations without gas challenges, …

… gas challenge and independent component analysis (ICA), we sought to improve the sensitivity
and speed of existing oxygen enhanced MRI (OE-MRI… of the physiological response. The …

… Familiarising the participants with the gas challenge prior to the CVR scan is essential to
avoid anxiety and to minimise differences in baseline physiological state between repeated …

… BAT is obtained from the voxel-wise delay between the physiological (ie end-tidal CO 2
and … The order of the concomitant and single-gas challenges was randomized and …