… using hyperpolarized 129Xe MRI for imaging of ventilation, alveolar‐airspace size, and gas exchange: A position paper from the 129Xe MRI clinical trials consortium

PJ Niedbalski, CS Hall, M Castro… - Magnetic resonance …, 2021 - Wiley Online Library
… dosing, acquisition order, physiologic monitoring, and imaging of the different HP 129 Xe …
biomarkers but may currently be overly challenging to widely implement due to hardware, …

Intracranial tumor response to respiratory challenges at 3.0 T: impact of different methods to quantify changes in the MR relaxation rate R2

A Müller, S Remmele, I Wenningmann… - … Resonance Imaging, 2010 - Wiley Online Library
… First, in order to evaluate both methods over a large physiological range of data, we …
challenges, we investigated the response to four different mixtures of O 2 and CO 2 breathing gases. …

Imaging tumour hypoxia with oxygen-enhanced MRI and BOLD MRI

JPB O'Connor, SP Robinson… - The British journal of …, 2019 - academic.oup.com
… design is more challenging because of the need to interpret the physiological effects of both
O … 1 and R 2 * gas-challenge MRI will be to demonstrate readily measurable and consistent …

Hyperpolarized 129Xe MR Imaging of Alveolar Gas Uptake in Humans

ZI Cleveland, GP Cofer, G Metz, D Beaver, J Nouls… - PloS one, 2010 - journals.plos.org
… to examine regional pulmonary gas exchange is challenging, because the low density …
physiological factors on signal intensity. However, our results suggest that dissolved 129 Xe MRI

Oxygen‐enhanced MRI of the brain

C Losert, M Peller, P Schneider… - Magnetic Resonance in …, 2002 - Wiley Online Library
… (BOLD) contrast MRI is a potential method for a physiological … examinations using a hyperoxia
challenge. Administration of … The gases that are used as a hyperoxia challenge differ in …

Benchmarking transverse spin relaxation based oxygenation measurements in the brain during hypercapnia and hypoxia

WW Ni, T Christen, G Zaharchuk - … of Magnetic Resonance …, 2017 - Wiley Online Library
… Our gas delivery setup achieved stable gas challenges as shown by physiological monitoring.
Test–retest variability of … Rigorous physiological monitoring in this study validated our gas

Feasibility of 4D T2* quantification in the lung with oxygen gas challenge in patients with non-small cell lung cancer

K Breuer, S Weick, SP Ströhle, FA Breuer, P Kleine… - Physica Medica, 2020 - Elsevier
… Blood oxygen level-dependent (BOLD) MRI is a non-invasive diagnostic method for … of the
tumour after gas challenge under consideration of physiological changes. The comparison of …

High temporal resolution MRI quantification of global cerebral metabolic rate of oxygen consumption in response to apneic challenge

ZB Rodgers, V Jain, EK Englund… - Journal of Cerebral …, 2013 - journals.sagepub.com
… Because the SSS receives venous blood from most of the cortex, this assumption should
be valid, especially during global physiologic challenges such as apnea or gas mixture …

Quantitative functional MRI: concepts, issues and future challenges

GB Pike - Neuroimage, 2012 - Elsevier
… to our understanding of brain physiology, human CBV monitoring … measured with PET and
MRI techniques sensitive to total … and poorly controlled end-tidal gases that result from F i CO …

A portable ventilator with integrated physiologic monitoring for hyperpolarized 129Xe MRI in rodents

RS Virgincar, J Dahlke, SH Robertson… - Journal of Magnetic …, 2018 - Elsevier
… and portable HP gas ventilator that integrates all the gas-delivery and physiologic monitoring
… 500 ml for humans), which challenges both the precision of gas delivery and the spatial …