Altered stress-induced regulation of genes in monocytes in adults with a history of childhood adversity

M Schwaiger, M Grinberg, D Moser, J Zang… - …, 2016 - nature.com
… For the analyses of group differences in stress-induced gene expression changes, only
transcripts that showed a difference in gene expression between the pre-stress and either post-…

Stress genomics revisited: gene co-expression analysis identifies molecular signatures associated with childhood adversity

L Dieckmann, S Cole, R Kumsta - Translational psychiatry, 2020 - nature.com
adversity, and investigated basal gene expression profiles. Given the regulatory function of
stress system activation on immune gene expression, … adults reporting childhood adversity 10,…

Epigenetic mechanisms activated by childhood adversity

BJ Krause, R Artigas, AF Sciolla, J Hamilton - Epigenomics, 2020 - Taylor & Francis
… Furthermore, it is commonly accepted that increased DNA methylation in promoter
regions represents a hallmark of reduced gene expression and long-term gene silencing [Citation24]. …

Early adversity and the regulation of gene expression: implications for prenatal health

SL Gillespie, SW Cole, LM Christian - Current opinion in behavioral …, 2019 - Elsevier
… Early life, including prenatal development and childhood, is a period of sensitivity, with …
First, we review findings from gene expression studies examining the effects of early adversity on …

Childhood and later life stressors and increased inflammatory gene expression at older ages

ME Levine, SW Cole, DR Weir, EM Crimmins - Social science & medicine, 2015 - Elsevier
childhood exposure to adversity will be associated with more pronounced increase in
inflammatory gene expression … levels were only found to be associated with childhood adversity (…

The DNA methylation landscape of the human oxytocin receptor gene (OXTR): data-driven clusters and their relation to gene expression and childhood adversity

S Müller, M Sicorello, D Moser, L Frach… - Translational …, 2023 - nature.com
… between DNA methylation, childhood trauma and gene expression in the maternal … 4) to
contribute most strongly to the latent dimension predicting gene expression and CTQ scores. …

Enduring psychobiological effects of childhood adversity

U Ehlert - Psychoneuroendocrinology, 2013 - Elsevier
… result in lasting changes in BDNF gene expression and BDNF DNA methylation, prefrontal
… The authors reported not only a reduced BDNF gene expression within the adult prefrontal …

[HTML][HTML] Gene expression in cord blood links genetic risk for neurodevelopmental disorders with maternal psychological distress and adverse childhood outcomes

MS Breen, AP Wingo, N Koen, KA Donald… - Brain, Behavior, and …, 2018 - Elsevier
… elucidate whether these changes in gene expression also precede clinically recognizable
Child Health Study based in South Africa. We analyzed transcriptome-wide gene expression

Investigating the impact of early-life adversity on physiological, immune, and gene expression responses to acute stress: A pilot feasibility study

I Shalev, WJ Hastings, L Etzel, S Israel, MA Russell… - Plos one, 2020 - journals.plos.org
… During these sessions, we obtained repeated measurements of physiological reactivity,
gene expression of the glucocorticoid receptor (NR3C1), and plasma levels of pro-inflammatory …

Childhood adversity and DNA methylation of genes involved in the hypothalamus–pituitary–adrenal axis and immune system: Whole-genome and candidate-gene …

J Bick, O Naumova, S Hunter, B Barbot… - Development and …, 2012 - cambridge.org
… of gene expression involved in immune system responses. Differential regulation in genes
… with exposure to low socioeconomic conditions during childhood (Miller & Chen, 2007). …