Altered stress-induced regulation of genes in monocytes in adults with a history of childhood adversity
M Schwaiger, M Grinberg, D Moser, J Zang… - …, 2016 - nature.com
… For the analyses of group differences in stress-induced gene expression changes, only
transcripts that showed a difference in gene expression between the pre-stress and either post-…
transcripts that showed a difference in gene expression between the pre-stress and either post-…
Stress genomics revisited: gene co-expression analysis identifies molecular signatures associated with childhood adversity
L Dieckmann, S Cole, R Kumsta - Translational psychiatry, 2020 - nature.com
… adversity, and investigated basal gene expression profiles. Given the regulatory function of
stress system activation on immune gene expression, … adults reporting childhood adversity 10,…
stress system activation on immune gene expression, … adults reporting childhood adversity 10,…
Epigenetic mechanisms activated by childhood adversity
BJ Krause, R Artigas, AF Sciolla, J Hamilton - Epigenomics, 2020 - Taylor & Francis
… Furthermore, it is commonly accepted that increased DNA methylation in promoter
regions represents a hallmark of reduced gene expression and long-term gene silencing [Citation24]. …
regions represents a hallmark of reduced gene expression and long-term gene silencing [Citation24]. …
Early adversity and the regulation of gene expression: implications for prenatal health
SL Gillespie, SW Cole, LM Christian - Current opinion in behavioral …, 2019 - Elsevier
… Early life, including prenatal development and childhood, is a period of sensitivity, with …
First, we review findings from gene expression studies examining the effects of early adversity on …
First, we review findings from gene expression studies examining the effects of early adversity on …
Childhood and later life stressors and increased inflammatory gene expression at older ages
… childhood exposure to adversity will be associated with more pronounced increase in
inflammatory gene expression … levels were only found to be associated with childhood adversity (…
inflammatory gene expression … levels were only found to be associated with childhood adversity (…
The DNA methylation landscape of the human oxytocin receptor gene (OXTR): data-driven clusters and their relation to gene expression and childhood adversity
… between DNA methylation, childhood trauma and gene expression in the maternal … 4) to
contribute most strongly to the latent dimension predicting gene expression and CTQ scores. …
contribute most strongly to the latent dimension predicting gene expression and CTQ scores. …
Enduring psychobiological effects of childhood adversity
U Ehlert - Psychoneuroendocrinology, 2013 - Elsevier
… result in lasting changes in BDNF gene expression and BDNF DNA methylation, prefrontal
… The authors reported not only a reduced BDNF gene expression within the adult prefrontal …
… The authors reported not only a reduced BDNF gene expression within the adult prefrontal …
[HTML][HTML] Gene expression in cord blood links genetic risk for neurodevelopmental disorders with maternal psychological distress and adverse childhood outcomes
… elucidate whether these changes in gene expression also precede clinically recognizable
… Child Health Study based in South Africa. We analyzed transcriptome-wide gene expression …
… Child Health Study based in South Africa. We analyzed transcriptome-wide gene expression …
Investigating the impact of early-life adversity on physiological, immune, and gene expression responses to acute stress: A pilot feasibility study
… During these sessions, we obtained repeated measurements of physiological reactivity,
gene expression of the glucocorticoid receptor (NR3C1), and plasma levels of pro-inflammatory …
gene expression of the glucocorticoid receptor (NR3C1), and plasma levels of pro-inflammatory …
Childhood adversity and DNA methylation of genes involved in the hypothalamus–pituitary–adrenal axis and immune system: Whole-genome and candidate-gene …
… of gene expression involved in immune system responses. Differential regulation in genes
… with exposure to low socioeconomic conditions during childhood (Miller & Chen, 2007). …
… with exposure to low socioeconomic conditions during childhood (Miller & Chen, 2007). …
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