… The reduction of oxygen by less than four electrons leads to generation of unstable
metabolites that are called reactive oxygen species (ROS). Cellular ROS production can be …

Reactive oxygen species (ROS) are produced by cellular metabolic reactions, and have been
implicated in the pathogenesis of several diseases, including atherosclerosis, cancer, and …

… Reactive oxygen species not only regulate the activity of preexistingproteins, they also are
responsible for inducing the expression of many genes… concerted patternsof gene expression (…

… about the regulation of gene expression by ROS comes from studies on genes involved in
… However, in many cases, it is unclear whether the altered gene expression results directly …

… genes with important functional roles in the physiology and pathophysiology of vascular cells.
Thus, reactive oxygen species … -dependent relaxation and expression of a proinflammatory …

Reactive oxygen species (ROS) have long been considered as cytotoxic. However, recent
evidence indicates a prominent role of ROS as signaling molecules in the response to …

Vascular diseases are a major complication of diabetes mellitus (DM), although their etiology
is poorly understood. NADPH oxidase-derived reactive oxygen species (ROS) production …

… reactions, mitochondrial electron transport, signal transduction, activation of nuclear transcription
factors, gene expression, and the antimicrobial action of neutrophils and macrophages. …

… To examine the molecular mechanism for LPS induction of IL-1 in macrophages, we
demonstrated that LPS quickly stimulated reactive oxygen species (ROS), and 3 h later induced …

… cognate response element in the enhancers of genes encoding for erythropoietin (EPO), …
Reactive oxygen species (ROS) have been proposed to act as the signal between the oxygen …