The gene expression response of breast cancer to growth regulators: patterns and correlation with tumor expression profiles

HE Cunliffe, M Ringnér, S Bilke, RL Walker… - Cancer research, 2003 - AACR
… disease progression rather than growth factor signaling. This article highlights the overall
impact at the gene expression level of diverse regulators of breast cancer growth and links the …

Progranulin Gene Expression Regulates Epithelial Cell Growth and Promotes Tumor Growth in Vivo

Z He, A Bateman - Cancer research, 1999 - AACR
gene expression to maintain malignancy. Here we show that as well as requiring the gene
product, elevating progranulin gene expression … Epithelial tumors are thought to originate as …

Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth

PH Maxwell, GU Dachs, JM Gleadle… - Proceedings of the …, 1997 - National Acad Sciences
… in gene expression, vascularity, and growth between the tumortumors is appropriate for
HIF-1 activation, and that this has an … function in determining tumor angiogenesis and growth. …

PGC1α promotes tumor growth by inducing gene expression programs supporting lipogenesis

K Bhalla, BJ Hwang, RE Dewi, L Ou, W Twaddel… - Cancer research, 2011 - AACR
… loss of PGC1α expression showed that PGC1α also promotes tumor growth. Interestingly, …
cycle gene expression, we also observed an increase in the expression of two genes required …

Tumor growth modulation by sense and antisense vascular endothelial growth factor gene expression: effects on angiogenesis, vascular permeability, blood volume …

T Oku, JG Tjuvajev, T Miyagawa, T Sasajima, A Joshi… - Cancer research, 1998 - AACR
tumor angiogenesis and tumor growth. We evaluated the effect of VEGF expression on the
pathophysiology of tumor growth in … , with minimal VEGF expression, were stably transfected …

The von Hippel–Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C

X Niu, T Zhang, L Liao, L Zhou, DJ Lindner, M Zhou… - Oncogene, 2012 - nature.com
… To investigate whether this would promote or suppress tumor growth, we compared the
growth … As reported, expression of pVHL did not affect the 786-O cells growth under standard …

Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1α enhances hypoxic gene expression and tumor growth

AJ Krieg, EB Rankin, D Chan… - … and cellular biology, 2010 - Taylor & Francis
tumor growth in vivo, demonstrating that histone demethylation plays a significant role in
modulating growth within the tumorgene expression, ultimately enhancing tumor growth. …

[HTML][HTML] Gene expression profiling of the tumor microenvironment during breast cancer progression

XJ Ma, S Dahiya, E Richardson, M Erlander… - Breast cancer …, 2009 - Springer
… -associated stroma is activated by the malignant epithelial cells to foster tumor growth – for
example, by secreting growth factors, increasing angiogenesis, and facilitating cell migration, …

Modulation of gene expression and tumor cell growth by redox modification of STAT3

L Li, S Cheung, EL Evans, PE Shaw - Cancer research, 2010 - AACR
gene expression The effect of ROS on STAT3-dependent gene expression was examined
with reporter genes … yielded low levels of IL-6–inducible expression. Cotransfection of an …

Differentiation and gene expression profile of tumor-associated macrophages

A Schmieder, J Michel, K Schönhaar, S Goerdt… - Seminars in cancer …, 2012 - Elsevier
tumors infiltrated with Fn1 expressing TAM. Other matrix remodelling functions in support of
tumor growth mediated by TAMs is expression … -regulation of mRNA for the genes MMP-1, -2, …