… as DNA methyltransferases. Importantly, DNA methylation is related to the regulation of gene
… -chromosome inactivation, genetic imprinting, and the repression of transposable elements. …

… Methylation of DNA cytosine bases leads to the inaccessibility of DNA regulatory elements
… Our understanding of DNA methylation has advanced rapidly in recent years with the …

… act in gene regulation. We show that unlike genetic regulatory variation, DNA methylation
alone … Finally, inferred mechanistic relationships using genetic variation as well as correlations …

… groups are added to DNA molecules which changes the activity of the DNA segments. This
… of genetic uses. This issue explores DNA methylation in cancer, the role of DNA methylation …

… Repression of developmental gene regulation has been shown to be regulated by Polycomb
group proteins.46 A hallmark for Polycomb-mediated repression is H3K27Me3 which is set …

… modification may be involved in gene regulation, they did not prove that methylation of a
geneis the direct cause of its suppression. To evaluate this question, it was imperative to turn to …

… novo DNA methylation has provided a framework for an RNA-dependent DNA methylation
process … Although DRM1/2 are clearly essential for perpetuation of non-CG methylation, it is …

… two global mechanisms of gene regulation, DNA methylation and histone deacetylation, can
be linked by MeCP-2.61,62 However, in some instances DNA methylation has been shown …

… role of DNA methylation in gene regulation (… gene activity and DNA methylation. Based on
the informa tion gleaned from the experiments discussed, one can argue that DNA methylation …

… The decisive steps in gene regulation probably involve the interaction of DNA and proteins
in the chromatin structure. DNA methylation, with the methyl group probably in the major …