Non-canonical functions of the DNA methylome in gene regulation
JP Reddington, S Pennings, RR Meehan - Biochemical Journal, 2013 - portlandpress.com
… manner by which DNA methylation influences gene regulation at the molecular level, and
which genes rely directly on the DNA methylome for their normal transcriptional regulation. It is …
which genes rely directly on the DNA methylome for their normal transcriptional regulation. It is …
[HTML][HTML] The DNA methylome
M Pelizzola, JR Ecker - FEBS letters, 2011 - Elsevier
… This is particularly critical for TFs, given that they bind upstream gene regulatory regions,
where DNA methylation has always been considered a critical factor. Also, the relationship …
where DNA methylation has always been considered a critical factor. Also, the relationship …
Enhancer DNA methylation: implications for gene regulation
A Angeloni, O Bogdanovic - Essays in biochemistry, 2019 - portlandpress.com
… These important observations resulted in speculations of 5mC potentially acting as a dynamic
gene regulatory mechanism, with broad-reaching implications for embryogenesis and cell …
gene regulatory mechanism, with broad-reaching implications for embryogenesis and cell …
Mammalian DNA methylome dynamics: mechanisms, functions and new frontiers
… methylome analysis reveals that DNA methylation can be highly cell-type specific and dynamic
within proximal and distal gene regulatory … functions of regulated DNA methylation and …
within proximal and distal gene regulatory … functions of regulated DNA methylation and …
DNA methylation and regulation of gene expression: Guardian of our health
GA Dhar, S Saha, P Mitra, R Nag Chaudhuri - The Nucleus, 2021 - Springer
… on the offspring health can have manifold effects through regulation of the DNA methylome.
… Further experiments are needed to get a more comprehensive view of the gene regulatory …
… Further experiments are needed to get a more comprehensive view of the gene regulatory …
Human endometrial DNA methylome is cycle-dependent and is associated with gene expression regulation
S Houshdaran, Z Zelenko, JC Irwin… - Molecular …, 2014 - academic.oup.com
… DNA methylomes from the same samples revealed association of DNA methylation and
gene … and progesterone exhibited DNA methylation changes in several genes observed in …
gene … and progesterone exhibited DNA methylation changes in several genes observed in …
Passive and active DNA methylation and the interplay with genetic variation in gene regulation
… act in gene regulation. We show that unlike genetic regulatory variation, DNA methylation
alone … Human DNA methylomes at base resolution show widespread epigenomic differences. …
alone … Human DNA methylomes at base resolution show widespread epigenomic differences. …
New guidelines for DNA methylome studies regarding 5-hydroxymethylcytosine for understanding transcriptional regulation
… Many DNA methylome profiling methods cannot distinguish … between gene expression and
the two forms of DNA methylation at … We find that 5mC and 5hmC signals correlate with gene …
the two forms of DNA methylation at … We find that 5mC and 5hmC signals correlate with gene …
[PDF][PDF] Dependency of the cancer-specific transcriptional regulation circuitry on the promoter DNA methylome
… the cancer type-dependent gene regulatory machinery, we quantitatively assessed the
contributions of the regulatory circuits in the MeTRNs in gene expression regulation. Our results …
contributions of the regulatory circuits in the MeTRNs in gene expression regulation. Our results …
Simultaneous profiling of transcriptome and DNA methylome from a single cell
… DNA methylome and transcriptome from the same cell. In sensory neurons, we consistently
identify transcriptome and methylome … dissect the mechanisms of epigenetic gene regulation. …
identify transcriptome and methylome … dissect the mechanisms of epigenetic gene regulation. …
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