… The germ cell lineage transmits genetic and epigenetic information to the next generation.
Primordial germ cells (PGCs), the early embryonic precursors of sperm or eggs, have been …

… Germ cells hold a unique place in the life cycle of animal species in that they are the cells that
will carry the genome on to the next generation… , the germ cells are the only cells that retain …

… Most is known of the genes that control germ cell formation from systematic genetic screens
in invertebrates. In Drosophila and C. elegans, maternal effect mutations, in which the …

… for the study of germ cell development and the associated … into cells of all three germ
layers, and it is from these differentiating aggregates of cells that putative primordial germ cells (…

… other cell lineages (eg, neural cells), the generation of germ cells is not an “inductive” strategy
that is easily controlled by researchers. In recent years, however, trials towards germ-cell …

… Overall, our results strongly suggest that germ cells derived from donor PGCs predominate
… of the host germ cells has been blocked. To determine whether the germ cells in the gonad of …

… of generation in which reproductive cells develop in the plant body ("sporophytic generation")
and then differentiate into a multicellular gamete-forming "gametophytic generation." …

… germ cells. In this review the different methods used for the in vitro generation of germ cells
… improved and applied to further advance our knowledge of germ-cell biology are discussed. …

… Generation of germ cells from EG or ES cells may provide a model to address biological
questions of germ cell … The findings suggest that a niche develops from EG/ES cells during EB …

… capable of creating endless new generations through germ cells. PGCs are specified
during … of genetic and epigenetic information to subsequent generations. In this Primer, we …