[HTML][HTML] DNA methylation, its mediators and genome integrity

H Meng, Y Cao, J Qin, X Song, Q Zhang… - … journal of biological …, 2015 - ncbi.nlm.nih.gov
… of DNA methylation in shaping chromatin structure places its association with genome
integrity in … -stranded regions of DNA occurs at least 100-fold more rapidly than in double-stranded …

Making it or breaking it: DNA methylation and genome integrity

A Sriraman, TK Debnath, B Xhemalce… - Essays in …, 2020 - portlandpress.com
… are identified, how chemical modifications to DNA impact the DDR is poorly understood. …
of DNA methylation in maintaining genome integrity in mammalian cells. DNA methylation is a …

Sperm global DNA methylation level: association with semen parameters and genome integrity

D Montjean, A Zini, C Ravel, S Belloc, A Dalleac… - …, 2015 - Wiley Online Library
DNA methylation, semen parameters, and genome integrity. For this purpose, we have extracted
genomic DNA … Global DNA methylation level was estimated using an ELISA-like method …

Role of DNA methylation in genome stability

D Zhou, KD Robertson - Genome stability, 2016 - Elsevier
… namely DNA-methylation and histone modifications, are established and acknowledged as
contributing factors for maintaining genome integrity … In this chapter, we focus on the genomic

RNAi suppression of DNA methylation affects the drought stress response and genome integrity in transgenic poplar

MD Sow, AL Le Gac, R Fichot, S Lanciano… - New …, 2021 - Wiley Online Library
… Our findings suggest major roles for DNA methylation in regulation of genes involved in
hormone-related stress responses, and the maintenance of genome integrity through repression …

Genomic patterns of DNA methylation: targets and function of an epigenetic mark

M Weber, D Schübeler - Current opinion in cell biology, 2007 - Elsevier
DNA methylation on a genome-wide scale have given new insights into the biological function
of DNA methylation in maintaining genome integrity … focus on aberrant DNA methylation in …

[HTML][HTML] DNA methylation is required to maintain both DNA replication timing precision and 3D genome organization integrity

Q Du, GC Smith, PL Luu, JM Ferguson, NJ Armstrong… - Cell Reports, 2021 - cell.com
DNA hypomethylation, affects higher-order levels of genome … -C, we show that genome-wide
methylation loss is associated … and deregulation of 3D genome organization. Notably, we …

[HTML][HTML] Patterns of reliability: assessing the reproducibility and integrity of DNA methylation measurement

K Sugden, EJ Hannon, L Arseneault, DW Belsky… - Patterns, 2020 - cell.com
… Although DNA methylation data are used widely by researchers in many fields, the reliability
… We hope that our findings will improve the integrity of DNA methylation studies. We also …

[HTML][HTML] Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity

T Dahlet, A Argüeso Lleida, H Al Adhami… - Nature …, 2020 - nature.com
… multiple functions of DNA methylation in maintaining the transcription integrity of mouse
embryos. These results contribute to our understanding of why DNA methylation is essential for …

[HTML][HTML] Role of histone methylation in maintenance of genome integrity

A Mushtaq, US Mir, CR Hunt, S Pandita, WW Tantray… - Genes, 2021 - mdpi.com
… In this review, we highlight and discuss how histone methylation impacts the maintenance
of genome integrity through effects related to DNA repair and repair pathway choice. …