Profiling genome-wide DNA methylation

WS Yong, FM Hsu, PY Chen - Epigenetics & chromatin, 2016 - Springer
… In this review, we surveyed major methylation assays, along with comparisons and … their
strengths and weaknesses and perform comparisons across the different platforms. Due to the …

Principles and challenges of genome-wide DNA methylation analysis

PW Laird - Nature Reviews Genetics, 2010 - nature.com
… There has been a revolution in DNA methylation analysis technology … DNA methylation
profiling techniques that it can be challenging to select one. This Review discusses the different

Quantitative comparison of genome-wide DNA methylation mapping technologies

C Bock, EM Tomazou, AB Brinkman, F Müller… - Nature …, 2010 - nature.com
… points DNA methylation difference in the same way as for RRBS, the number of Infinium-detected
DMRs dropped to 162 (ES-cell comparison) and 95 (colon cancer comparison). In …

Genome-wide DNA methylation comparison between live human brain and peripheral tissues within individuals

PR Braun, S Han, B Hing, Y Nagahama… - Translational …, 2019 - nature.com
Differential DNA methylation in the brain is associated with many psychiatric diseases, but
access to brain tissues is essentially limited to postmortem samples. The use of surrogate …

Genomewide DNA methylation profiling

M Bibikova, JB Fan - Wiley Interdisciplinary Reviews: Systems …, 2010 - Wiley Online Library
… one, which substantially improved the sensitivity of detecting DNA methylation differences. …
the effect of various DNA methylation mutants on genome-wide methylation patterns, and …

Genome-wide DNA methylation differences between late-onset Alzheimer's disease and cognitively normal controls in human frontal cortex

KM Bakulski, DC Dolinoy, MA Sartor… - Journal of …, 2012 - content.iospress.com
… on a genome-wide scale to … genome-wide DNA methylation profiles between 12 LOAD
and 12 cognitively normal age- and gender-matched subjects. Quantitative DNA methylation is …

[HTML][HTML] Genome-wide mapping of DNA methylation: a quantitative technology comparison

C Bock, EM Tomazou, A Brinkman, F Müller… - Nature …, 2010 - ncbi.nlm.nih.gov
Genome-wide DNA methylation mapping is most commonly used for detecting DNA
methylation differences, for example between diseased and healthy tissue or between genetically …

Exploring genome-wide DNA methylation profiles altered in hepatocellular carcinoma using Infinium HumanMethylation 450 BeadChips

J Shen, S Wang, YJ Zhang, HC Wu, MG Kibriya… - Epigenetics, 2013 - Taylor & Francis
DNA methylation differences obtained from genome-wide analyses. They suggested the
exclusion of CpG sites that overlap with SNPs or are located within CNVs regions according to …

Genomewide DNA methylation profiles in hepatocellular carcinoma

J Shen, S Wang, YJ Zhang, M Kappil, HC Wu… - …, 2012 - Wiley Online Library
… differentially methylated between tumor and adjacent nontumor tissues. A significant difference
… A volcano plot displayed mean DNA-methylation differences for all 26,486 CpG sites. A …

Comparison of the genome-wide DNA methylation profiles between fast-growing and slow-growing broilers

Y Hu, H Xu, Z Li, X Zheng, X Jia, Q Nie, X Zhang - PloS one, 2013 - journals.plos.org
… and avian broiler using Methylated DNA immunoprecipitation-sequencing (MeDIP-seq) [23]. …
the genome-wide DNA methylation pattern in the muscle and to identify methylated genes …