Genome-wide DNA methylation profiling using Infinium® assay

M Bibikova, J Le, B Barnes, S Saedinia-Melnyk… - …, 2009 - Taylor & Francis
… Moreover, tissue-specific methylation (variation in methylation across tissues) was much …
Conclusion: Our results demonstrate a genome-wide scalable array-based methylation readout …

Profiling genome-wide DNA methylation

WS Yong, FM Hsu, PY Chen - Epigenetics & chromatin, 2016 - Springer
… In this review, we surveyed major methylation assays, … of DNA methylation profiling
techniques. The advances in microarray and sequencing technologies make genome-wide profiling

methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles

A Akalin, M Kormaksson, S Li, FE Garrett-Bakelman… - Genome biology, 2012 - Springer
DNA methylation is a chemical modification of cytosine bases that is pivotal for gene … ,
thatrapidly analyzes genome-wide cytosine epigenetic profiles from high-throughput methylation

Genomewide DNA methylation profiling

M Bibikova, JB Fan - Wiley Interdisciplinary Reviews: Systems …, 2010 - Wiley Online Library
methylated cytosines. With the development of next-generation sequencing technologies,
genome-wide … to get the most comprehensive DNA methylation profiles in organisms of various …

Exploring genome-wide DNA methylation profiles altered in hepatocellular carcinoma using Infinium HumanMethylation 450 BeadChips

J Shen, S Wang, YJ Zhang, HC Wu, MG Kibriya… - Epigenetics, 2013 - Taylor & Francis
… was to discover novel genome-wide aberrant DNA methylation patterns in HCC tumors that
… arrays were used to examine genome-wide DNA methylation profiles in 66 pairs of HCC …

Principles and challenges of genome-wide DNA methylation analysis

PW Laird - Nature Reviews Genetics, 2010 - nature.com
… -base-pair resolution whole-genome DNA methylation analysis 22,23,24 . Many of the
high-resolution genome-wide DNA methylation profiling techniques were pioneered in model …

Genomewide DNA methylation profiles in hepatocellular carcinoma

J Shen, S Wang, YJ Zhang, M Kappil, HC Wu… - …, 2012 - Wiley Online Library
… Data on survival were not available for most of our cases, so we were unable to investigate
methylation profile and survival. We also determined whether methylation of a random subset …

Genomewide DNA methylation profiles in precancerous conditions and cancers

Y Kanai - Cancer science, 2010 - Wiley Online Library
DNA methylation status is not simply altered at the precancerous stage; rather, DNA methylation
… Therefore, genome-wide DNA methylation profiling may provide optimal indicators for …

Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact

WG Tong, WG Wierda, E Lin, SQ Kuang, BN Bekele… - Epigenetics, 2010 - Taylor & Francis
… a useful tool to study the genome-wide DNA methylation profile in leukemia or other cancer
… of aberrant DNA methylation in patients with CLL that carry 17p deletion. Methylation status …

Genome-wide DNA methylation profiling using the methylation-dependent restriction enzyme LpnPI

R Boers, J Boers, B de Hoon, C Kockx, Z Ozgur… - Genome …, 2018 - genome.cshlp.org
… to interrogate DNA methylation genome wide, but … of methylated CpG-rich templates. Here,
we tested a third MspJI family member, LpnPI, and compared genome-wide DNA methylation