Genomic DNA methylation: the mark and its mediators

RJ Klose, AP Bird - Trends in biochemical sciences, 2006 - cell.com
… When double-stranded RNA corresponding to the promoter sequence of a gene is …
concomitant with de novo DNA methylation of the corresponding promoter sequence. There is some …

Direct detection of methylation in genomic DNA

A Bart, MWJ van Passel, K Van Amsterdam… - Nucleic acids …, 2005 - academic.oup.com
… suffices to detect methylated sites in genomic DNA. In … natural types of DNA methylation
in bacterial genomic DNA. This … of DNA methylation by direct sequencing to prokaryotic total …

DNA methylation

R Singal, GD Ginder - Blood, The Journal of the American …, 1999 - ashpublications.org
Genomic sequencing protocols that have previously been used to study DNA methylation
use Maxam and Gilbert chemical cleavage reactions performed on genomic DNA33 with linker-…

DNA methylation detection: bisulfite genomic sequencing analysis

Y Li, TO Tollefsbol - Epigenetics protocols, 2011 - Springer
sequencing analysis can not only indentify DNA methylation status along the DNA single
strand, but also detect the DNA methylation … (6), genomic DNA is denatured in high sodium …

Genomic patterns of DNA methylation: targets and function of an epigenetic mark

M Weber, D Schübeler - Current opinion in cell biology, 2007 - Elsevier
… enrichments than methylated CpG-poor sequences. … DNA methylation or DNA methylation
of individual repetitive elements. Bisulfite genomic sequencing to determine DNA methylation

CyMATE: a new tool for methylation analysis of plant genomic DNA after bisulphite sequencing

J Hetzl, AM Foerster, G Raidl, OM Scheid - The Plant Journal, 2007 - Wiley Online Library
… To generate data suitable for analysis with CyMATE, we analysed the DNA methylation state
at a transgenic insert in genomic DNA of Arabidopsis thaliana, consisting of the hygromycin …

Decline in genomic DNA methylation through aging in a cohort of elderly subjects

V Bollati, J Schwartz, R Wright, A Litonjua… - Mechanisms of ageing …, 2009 - Elsevier
DNA methylation was measured using quantitative PCR-Pyrosequencing analysis in Alu …
, heavily methylated sequences with high representation throughout the human genome. …

Whole genome DNA methylation analysis based on high throughput sequencing technology

N Li, M Ye, Y Li, Z Yan, LM Butcher, J Sun, X Han… - Methods, 2010 - Elsevier
… to highly methylated, high-CpG densities and MDB-seq more sensitive to highly methylated,
… account the size of a mammalian genome and the current expense of sequencing, we feel 3 …

DNA-methylation analysis by the bisulfite-assisted genomic sequencing method

P Hajkova, O El-Maarri, S Engemann, J Oswald… - DNA methylation …, 2002 - Springer
… of methylation sites in the genomic DNA, as only methylated cytosines are … DNA can be
used directly for sequencing (detection of average methylation status) or cloned and sequenced

Genomic sequencing.

GM Church, W Gilbert - Proceedings of the National …, 1984 - National Acad Sciences
DNA Methylation. Up to 12% of all cytosines in vertebrate genomes are methylated
mainly at CG sequences… By determining the sequence of genomic DNA with the single-base-specific …