The methylome: approaches for global DNA methylation profiling

S Beck, VK Rakyan - Trends in Genetics, 2008 - cell.com
DNA methylation plays a critical role in genome function both in … DNA methylation plays a
role in disease, the first high-resolution DNA methylation profile (or methylome) of any genome

Profiling DNA methylation patterns using genomic tiling microarrays

Z Lippman, AV Gendrel, V Colot, R Martienssen - Nature methods, 2005 - nature.com
… of eukaryotic genomes that comprise primarily repetitive DNA … and enriched in DNA
methylation and methylation of histone … Furthermore, aberrant DNA methylation is associated with …

Charting a dynamic DNA methylation landscape of the human genome

MJ Ziller, H Gu, F Müller, J Donaghey, LTY Tsai… - Nature, 2013 - nature.com
… of genomic CpGs changes its methylationDNA methylation state of most human autosomal
CpGs to determine those that show dynamic changes and hence may participate in genome

[HTML][HTML] Comparative whole genome DNA methylation profiling across cattle tissues reveals global and tissue-specific methylation patterns

Y Zhou, S Liu, Y Hu, L Fang, Y Gao, H Xia… - BMC biology, 2020 - Springer
DNA controls supported that we faithfully captured patterns of genomic DNA methylation in
… Moreover, we detected low non-CG methylation in the non-brain somatic tissues and sperm …

Effects of X-ray irradiation on genomic DNA methylation levels in mouse tissues

R Tawa, Y Kimura, JI Komura… - Journal of radiation …, 1998 - ieeexplore.ieee.org
… Effects of ionizing radiation on the level of genomic DNA methylation in liver, brain and spleen
of … The data indicate that radiation-induced alteration in genomic DNA methylation is not …

Prenatal Exposure to Polycyclic Aromatic Hydrocarbons, Benzo[a]pyrene–DNA Adducts, and Genomic DNA Methylation in Cord Blood

JB Herbstman, D Tang, D Zhu, L Qu… - Environmental …, 2012 - ehp.niehs.nih.gov
… exposure, resulting in both increased PAH–DNA adducts and altered DNA methylation. …
is associated with genomic DNA methylation in cord blood and whether methylation levels are …

Genome-wide evolutionary analysis of eukaryotic DNA methylation

A Zemach, IE McDaniel, P Silva, D Zilberman - Science, 2010 - science.org
… , and the extent of methylation biology conservation is unclear. We quantified DNA methylation
in 17 eukaryotic genomes and found that gene body methylation is conserved between …

Notes on the role of dynamic DNA methylation in mammalian development

TH Bestor, JR Edwards… - Proceedings of the …, 2015 - National Acad Sciences
DNA methylation does have essential roles in irreversible promoter silencing, as in the …
have either methylated or unmethylated genomes, DNA methylation endows genomes with the …

DNA methylation and gene expression

Z Siegfried, I Simon - Wiley Interdisciplinary Reviews: Systems …, 2010 - Wiley Online Library
… .8,9 However, DNA methylation may have different … genome into island and non-island
regions still holds true. However, recent advances in measuring genome-wide DNA methylation (…

[HTML][HTML] Reversing DNA methylation: mechanisms, genomics, and biological functions

H Wu, Y Zhang - Cell, 2014 - cell.com
… or DNA glycosylase-initiated base excision repair. In this review, we discuss the mechanism
and function of DNA demethylation in mammalian genomes, … reversal of DNA methylation in …