The developmental epigenomics toolbox: ChIP-seq and MethylCap-seq profiling of early zebrafish embryos

O Bogdanović, A Fernández-Miñán, JJ Tena… - Methods, 2013 - Elsevier
… -regulated DNA methylation remodeling … DNA methylation studies of early zebrafish
development rendering this method highly suitable for the global assessment of DNA methylation in …

Dynamics of DNA hydroxymethylation in zebrafish

JH Kamstra, M Løken, P Aleström, J Legler - Zebrafish, 2015 - liebertpub.com
… hmC is not present during early zebrafish development, 16,21 … Even though the DNA
methylation level in the zebrafish … maternal genome leads to, our results show a lower methylation

Zebrafish embryos as a screen for DNA methylation modifications after compound exposure

MC Bouwmeester, S Ruiter, T Lommelaars… - Toxicology and applied …, 2016 - Elsevier
… In conclusion, the zebrafish embryo is a potential screening tool to examine DNA methylation
modifications after xenobiotic exposure. The next step is to examine the adult phenotype of …

DNA methylation and histone modifications are essential for regulation of stem cell formation and differentiation in zebrafish development

AD Marchione, Z Thompson… - … in functional genomics, 2021 - academic.oup.com
… , including methylation and acetylation of specific lysine (K) residues, are established on
histones [3]. Genomes undergo global methylation changes to stabilize DNA methylation levels …

Ionizing radiation induces transgenerational effects of DNA methylation in zebrafish

JH Kamstra, S Hurem, LM Martin, LC Lindeman… - Scientific reports, 2018 - nature.com
… We included a list of empirically derived developmental stage specific DMR (dsDMRs) that
are dynamically methylated during early zebrafish development 63 , and a computationally …

Embryonic DNA methylation: insights from the genomics era

O Bogdanović… - … in functional genomics, 2014 - academic.oup.com
… While the bulk of genomic DNA methylation is static throughout the mammalian life cycle,
global DNA methylation erasure and re-establishment can be observed during early …

Packaging development: how chromatin controls transcription in zebrafish embryogenesis

JA Horsfield - Biochemical Society Transactions, 2019 - portlandpress.com
… transcriptional programmes during early zebrafish development, patterning and … DNA
methylation patterns of the two parental genomes by passively deterring DNA methylation

Molecular evolution of zebrafish dnmt3 genes and thermal plasticity of their expression during embryonic development

C Campos, LMP Valente, JMO Fernandes - Gene, 2012 - Elsevier
… In mammals, proper patterns of DNA methylation are essential not only for … DNA methylation
reprogramming has been investigated. Significant differences in genome DNA methylation

Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling

Y Chernyavskaya, R Mudbhary, C Zhang… - …, 2017 - journals.biologists.com
… Both sources of DNA increased the number of macrophages … that genomic DNA from whole
embryos contains cells with varying amounts of DNA methylation and thus the genomic DNA

A role for DNA methylation in gastrulation and somite patterning

CC Martin, L Laforest, MA Akimenko, M Ekker - Developmental biology, 1999 - Elsevier
… Global changes in DNA methylation during early zebrafish development. … into a relative
increase in genome DNA methylation. Following fertilization, the diploid genome of the early …