Ionising radiation induces promoter DNA hypomethylation and perturbs transcriptional activity of genes involved in morphogenesis during gastrulation in zebrafish
S Murat El Houdigui, C Adam-Guillermin… - International Journal of …, 2020 - mdpi.com
… To assess whether IR can modify epigenetic marks and thereby modulate transcriptional
activity, we analysed DNA methylation at the whole genome scale using WGBS on shield stage …
activity, we analysed DNA methylation at the whole genome scale using WGBS on shield stage …
Histone modifications in zebrafish development
VT Cunliffe - Methods in Cell Biology, 2016 - Elsevier
… and DNA methylation… genome sequencing technology to generate DNA sequence data
from chromatin immunoprecipitates. I also discuss computational approaches to integrating DNA …
from chromatin immunoprecipitates. I also discuss computational approaches to integrating DNA …
[HTML][HTML] UHRF1 regulation of Dnmt1 is required for pre-gastrula zebrafish development
… largely mediate maintenance DNA methylation and Uhrf1 is … modifiers regulate early zebrafish
development and … , we conclude that bulk DNA methylation is not the primary mechanism. …
development and … , we conclude that bulk DNA methylation is not the primary mechanism. …
Differential DNA methylation at conserved non-genic elements and evidence for transgenerational inheritance following developmental exposure to mono (2 …
… Our results suggest a functional role for DNA methylation on cis-regulatory conserved
elements following developmental exposure to compounds. Effects on these regions are …
elements following developmental exposure to compounds. Effects on these regions are …
Transgenerational inheritance of impaired larval T cell development in zebrafish
N Iwanami, DF Lawir, K Sikora, CO´ Meara… - Nature …, 2020 - nature.com
… of aberrant DNA methylation patterns associated with impaired larval T cell development. …
Moreover, DMRs exhibiting dynamic changes during early zebrafish development, such as …
Moreover, DMRs exhibiting dynamic changes during early zebrafish development, such as …
Transcriptional activity and DNA methylation dynamics of the Gal4/UAS system in zebrafish
SC Pang, HP Wang, ZY Zhu, YH Sun - Marine Biotechnology, 2015 - Springer
… Moreover, we observed asymmetric DNA methylation of the 4xUAS sequence in oocytes …
Recent research studying methylation in early zebrafish development using whole-genome …
Recent research studying methylation in early zebrafish development using whole-genome …
Uracil-DNA glycosylase is involved in DNA demethylation and required for embryonic development in the zebrafish embryo
… causes an increase of the global DNA methylation level concomitantly with a reduction of …
DNA methylation level, to increase H3K4me3 and H3K27me3 marks, and to activate genome …
DNA methylation level, to increase H3K4me3 and H3K27me3 marks, and to activate genome …
Environmental epigenetics in zebrafish
V Cavalieri, G Spinelli - Epigenetics & chromatin, 2017 - Springer
… the genomic DNA methylation pattern throughout the embryonic body [84]. By means of
fluorescent immunostaining of 5-methylcytidine, the authors determined that, when compared to …
fluorescent immunostaining of 5-methylcytidine, the authors determined that, when compared to …
[HTML][HTML] Sperm, but not oocyte, DNA methylome is inherited by zebrafish early embryos
… DNA methylation pattern is maintained throughout early embryogenesis. The maternal DNA
methylation … We plotted the average DNA methylation level across the whole genome in …
methylation … We plotted the average DNA methylation level across the whole genome in …
Epigenetic effects of environmental chemicals: insights from zebrafish
N Aluru - Current opinion in toxicology, 2017 - Elsevier
… This review summarizes our current knowledge on the effects of environmental chemicals
on DNA methylation, histone modifications and noncoding RNAs in the context of DOHaD, and …
on DNA methylation, histone modifications and noncoding RNAs in the context of DOHaD, and …