Genomic location of PRMT6-dependent H3R2 methylation is linked to the transcriptional outcome of associated genes
C Bouchard, P Sahu, M Meixner, RR Nötzold, MB Rust… - Cell reports, 2018 - cell.com
… contribute to the transcriptional regulation of … genomic location, H3R2me2a possesses
either a repressive or activating nature: transcriptional repression at promoters and transcriptional …
either a repressive or activating nature: transcriptional repression at promoters and transcriptional …
Insights from genomic profiling of transcription factors
PJ Farnham - Nature Reviews Genetics, 2009 - nature.com
… outcome (perhaps under some specific condition or in a specific cell type) or whether some
transcription factor–genome … role of one specific binding site in its normal genomic context). …
transcription factor–genome … role of one specific binding site in its normal genomic context). …
A quantitative model of transcriptional regulation reveals the influence of binding location on expression
KD MacIsaac, KA Lo, W Gordon, S Motola… - PLoS computational …, 2010 - journals.plos.org
… called transcription factors that bind specific sites in the genome… transcription factors
interact with the cell's transcriptional … binding events and transcriptional outcomes can be quite …
interact with the cell's transcriptional … binding events and transcriptional outcomes can be quite …
Transcriptional outcomes and kinetic patterning of gene expression in response to NF-κB activation
… However, in the present study, we did not directly evaluate binding of such NF-κB-induced
transcription factors genome-wide. We will refer to such genes as indirect targets of RELA. In …
transcription factors genome-wide. We will refer to such genes as indirect targets of RELA. In …
Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci
… view, lncRNAs can act both post-transcriptionally and at the level of … transcription, where
they can affect genes in the immediate genomic vicinity (in cis) and/or in other genomic locations …
they can affect genes in the immediate genomic vicinity (in cis) and/or in other genomic locations …
Gastrointestinal stromal tumor enhancers support a transcription factor network predictive of clinical outcome
ML Hemming, MA Lawlor, R Zeid… - Proceedings of the …, 2018 - National Acad Sciences
… core transcription factors can be distinguished from others unique to localized and metastatic
disease. The transcription … The pattern of transcription factor expression in primary tumors is …
disease. The transcription … The pattern of transcription factor expression in primary tumors is …
Genomic localization of RNA binding proteins reveals links between pre-mRNA processing and transcription
… localize on the human genome three functionally distinct RNA … by reorganization of transcription
complexes as opposed to a … of the genome that provides insight into the transcriptional …
complexes as opposed to a … of the genome that provides insight into the transcriptional …
Functional analysis of transcription factor binding sites in human promoters
… transcription factors to specific locations in the genome is integral to the orchestration of
transcriptional … Our results suggest a transcriptional outcome for the co-localization of CTCF and …
transcriptional … Our results suggest a transcriptional outcome for the co-localization of CTCF and …
Prediction of genome-wide effects of single nucleotide variants on transcription factor binding
S Carrasco Pro, K Bulekova, B Gregor, A Labadorf… - Scientific Reports, 2020 - nature.com
… Single nucleotide variants (SNVs) located in transcriptional … outcomes. Here, we predict
gain or loss of binding sites for 741 transcription factors (TFs) across the human genome. We …
gain or loss of binding sites for 741 transcription factors (TFs) across the human genome. We …
A genomic code for nucleosome positioning
E Segal, Y Fondufe-Mittendorf, L Chen, AC Thåström… - Nature, 2006 - nature.com
… in immediately upstream or downstream locations, or to random genomic locations (light
blue)… varies with genomic location type and is low at functional transcription factor binding sites. …
blue)… varies with genomic location type and is low at functional transcription factor binding sites. …
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