In vivo epigenomic profiling of germ cells reveals germ cell molecular signatures
JH Ng, V Kumar, M Muratani, P Kraus, JC Yeo… - Developmental cell, 2013 - cell.com
… embryonic stem, and germ cells revealed promoters and enhancers needed for stem cell
maintenance and germ cell … germ cell cis-regulatory regions, and our results implicate Nr5a2 in …
maintenance and germ cell … germ cell cis-regulatory regions, and our results implicate Nr5a2 in …
Mitochondrial morphology in human fetal and adult female germ cells
PM Motta, SA Nottola, S Makabe, R Heyn - Human reproduction, 2000 - academic.oup.com
… The germinal component of the gonads (including the ovaries) originates from a small
number of primordial germ cells fPGCs) that are firstly detected in human embryos at the third …
number of primordial germ cells fPGCs) that are firstly detected in human embryos at the third …
The problem of the origin of germ cells
F Heys - The Quarterly Review of Biology, 1931 - journals.uchicago.edu
… germ cells in man. Thus it is admitted by many that the so-called primordial germ cells do
appear in early embryonic … From there they migrate to the genital ridge, such cells being the pre…
appear in early embryonic … From there they migrate to the genital ridge, such cells being the pre…
Generation of germ cells from pluripotent stem cells in mammals
M Hayashi, T Kawaguchi… - … medicine and biology, 2018 - Wiley Online Library
… The germ cell lineage transmits genetic and epigenetic information to the next generation.
Primordial germ cells (PGCs), the early embryonic precursors of sperm or eggs, have been …
Primordial germ cells (PGCs), the early embryonic precursors of sperm or eggs, have been …
Germ cell specification in mice
M Saitou - Current opinion in genetics & development, 2009 - Elsevier
… In mice, germ cell fate is induced in a subset of pluripotent … cells during early gastrulation.
Reflecting the function of the germ line as the transducer of genetic information, germ cell …
Reflecting the function of the germ line as the transducer of genetic information, germ cell …
Commitment of fetal male germ cells to spermatogonial stem cells during mouse embryonic development
H Ohta, T Wakayama, Y Nishimune - Biology of reproduction, 2004 - academic.oup.com
… cell activity of fetal germ cells in more detail, we transplanted fetal germ cells along with
infant germ cells labeled with GFP and compared their stem cell activities by differentially …
infant germ cells labeled with GFP and compared their stem cell activities by differentially …
Identification of genes controlling germ cell migration and embryonic gonad formation in Drosophila
LA Moore, HT Broihier, MV Doren, LB Lunsford… - …, 1998 - journals.biologists.com
… mutants demonstrates that germ cell migration can be … germ cells to form the embryonic
gonad. Moreover, mutations that we isolated affecting embryonic patterning as well as germ cell …
gonad. Moreover, mutations that we isolated affecting embryonic patterning as well as germ cell …
Turning germ cells into stem cells
PJ Donovan, MP de Miguel - Current opinion in genetics & development, 2003 - Elsevier
… to embryonal carcinoma cells, the pluripotent stem cells of … embryonic germ cells, pluripotent
stem cells that can contribute to all the lineages of chimeric embryos including the germline. …
stem cells that can contribute to all the lineages of chimeric embryos including the germline. …
Early germ cell segregation and distribution in the quail blastodisc
L Pardanaud, C Buck, F Dieterlen-Lièvre - Cell differentiation, 1987 - Elsevier
… for cells that we suspected to be primordi~ germ cells. Here we show that these cells are
indeed PGCs, and we repo~ a det~led quantitative ~udy of thor spatifl di~ribufion in the early …
indeed PGCs, and we repo~ a det~led quantitative ~udy of thor spatifl di~ribufion in the early …
Transcriptionally repressed germ cells lack a subpopulation of phosphorylated RNA polymerase II in early embryos of Caenorhabditis elegans and Drosophila …
G Seydoux, MA Dunn - Development, 1997 - journals.biologists.com
… in early embryonic germ cells. mAb H5 failed to stain germ cells entirely in both C. elegans
and Drosophila pregastrulation embryos. With mAb H14, some staining could be detected in …
and Drosophila pregastrulation embryos. With mAb H14, some staining could be detected in …