… the same donor. While the cases investigated in this study did not identify any evidence …
gonadal mosaicism, routine evaluation of DNA from sperm cells may help to identify mosaicism …

… donor, we confirmed the presence of a germline mosaicism in his spermatozoa. This finding
highlights the importance of germline mosaicism … the context of sperm donation, particularly …

… Here, we demonstrate that gonadal mosaic mutations detected in sperm from individual …
the presence of gonadal mosaic mutations identified in one sperm donor in the blastocysts of the …

… ular testing on DNA from semen samples is a significant limitation in the assessment of
germline mosaicism. IMPACT STATEMENT: Germline mosaicism and undiagnosed disease are …

… and 1 Icelandic offspring of donor number 7042 of whom … sperm donor with gonosomal
mosaicism for a NF1 deletion. To allow future follow-up, we have initiated The International Donor …

… mosaicism discovered in an anonymous sperm donor after receiving two reports of
neurofibromatosis type 1 (NF1) in donor-… a significant risk for gonadal mosaicism until the second …

… We found that gonadal mosaic variants showed significantly distinct mutational patterns (Figures
4B, S5A, and S5B; STAR Methods). For instance, C > G and T > C were depleted in all …

… among infertile males undergoing ICSI as compared to fertile donors (16). In other study we
demonstrated a linkage between gonadal failure (high serum FSH levels) and an increased …

… Here, we demonstrate that gonadal mosaic mutations detected in sperm from individual …
the presence of gonadal mosaic mutations identified in one sperm donor in the blastocysts of the …

… within an individual is termed as germline mosaicism. Germline mosaicism is a driving force
behind … Undoubtedly, this process may additionally be appropriate to sperm donor clinics. …