… normal cell to a cancer cell. Altered DNA methylation patterns in human cancer are not only
of … but may also may serve as markers for cancer diagnosis and prognosis, and prediction of …

… Like other neoplasms, the DNA methylation profile of hematological malignancies is …
hypermethylation of selected CpG island gene promoters [1], [2]. Both DNA hypermethylation and …

… DNA methylation is an epigenetic modification that can play an important role in the control
of gene expression. DNA methylation at … involved in DNA repair by uncontrolled methylation, …

… In this review, we will discuss normal and abnormal DNA methylation in hematopoietic cells,
… decreased DNA methylation has been described in some oncogenes in human tumors, the …

… Hypomethylated CGIs are enriched in genes related to hematologic malignancies such as
Prdm16, Stat1, Ccnd1, Myc, Mn1, Msi2, Men1, Erg, and Runx1. Changes in gene expression …

… I also wish that the iceberg is starting to melt and soon we will know the causes, profiles,
and translational uses of the aberrant DNA methylation present in hematologic malignancies. …

… interest in DNA methylation in cancer focused on the role of DNA … and haematological
malignancies, albeit rarely 1 , and reduced DNMT1 activity has been shown to promote cancer in …

… of lung cancer. In summary, targeting cancerassociated DNA hypermethylation provides
a … Role of epigenetic changes in hematological malignancies. Ann Hematol. 2004;83:137-152…

… To investigate whether the promoter regions of the genes differentially methylated in different
hematological tumors showed a specific CpG composition, we classified them into high (…

… lymphoid malignancies, and that DNA methylation of … DNA methylation in the PROX1 gene
is unclear. We will therefore screen for methylation of PROX1 in more lymphoid malignancies, …