Mammalian auditory hair cells do not spontaneously regenerate, unlike hair cells in lower
vertebrates, including fish and birds. In mammals, hearing loss due to the loss of hair cells is …

… A review of literature on the development of sensorineural hearing loss after high-dose
radiation therapy for head-and-neck tumors and stereotactic radiosurgery or fractionated …

… of hearing loss and they are a common target for therapeutic … patients suffering from hearing
loss has identified molecular … , genetic screening for common mutations is now feasible and …

… While peer-reviewed published data to directly support feasibility of hearing restoration of
longstanding hearing loss using Atoh1 gene is not available, the study was approved by the …

… and gene therapy. In this review we discuss recent developments in gene- and cell-based
therapy for hearing loss, including detailed analysis of therapeutic mechanisms such as RNA …

… and endogenous sources of hearing loss. Gene therapy technology is rapidly developing
and the inner ear is a particularly feasible model for gene therapy. This review outlines our …

… Gene therapy, or the treatment of human disease using … gene therapy treatments for
genetic hearing loss has … prospects, and challenges for gene therapy in the inner ear. We …

… therapy. Herein, we describe state-of-the-art research on genetic hearing loss treatment
through gene therapy … treatment may be more feasible for preventing subsequent hearing loss. …

… is to find a cure for the hearing loss that is caused by the loss of cochlear hair cells or spiral
… cell-replacement therapies for the damaged inner ear. The sense of hearing is integral to our …

… cause of acquired hearing loss. For the … of hearing loss as seen in humans and animal
models. Results from molecular studies are presented that have provided the basis for therapeutic …