… , we have investigated the promoter methylation status of nine … methylation-specific polymerase
chain reaction. We found that 82% of HCCs had methylation of at least one TSG promoter…

… , in hepatocellular carcinomas, aberrant methylation of several … or cirrhotic liver, promoter
methylation of several kinds of TSG, … (Table ​1 shows promoter methylation of different tumor-…

… (24%) to carcinoma in situ (50%). Aberrant promoter methylation of p16 and MGMT was also
detected by others in sputum DNA in 100% of patients with squamous cell carcinoma of the …

… methylated promoter DNA of all genes were significantly different in the various tissue types
except for MGMT. Our results suggest that promoter methylation … of promoter methylation in …

… Our results indicated that CDKN2A promoter methylation was associated with an enhancive
HCC risk and played a crucial role in the process of HCC with a potential value to being a …

… Core tip: DNA methylation of tumor suppressor gene promoter regions … hepatocellular
carcinoma (HCC). We found that aberrant serum metallothionein 1M (MT1M) promoter methylation …

… Using methylation-specific PCR, we demonstrated for the first time p15 promoter methylation
in 64% of … Concurrent p15and p16 methylation was shown in 48% of tumors, and p15/p16 …

… instability, while promoter DNA hypermethylation frequently … based on crossing DNA
methylation and gene expression … at investigating more specifically promoter methylation as a …

… The minimal promoter element contained four Sp1 binding sites, which were hypermethylated
in HCC cell-derived promoters. Moreover, analyses of Tip30 promoter methylation status …

… Then, we identified that known drivers in other tumors show aberrant promoter methylation
… In addition, we describe a landscape of aberrantly methylated promoters of genes potentially …