… by which vanillic acid regulates HIF-1α expression, we first examined the effect of vanillic
acid on HIF-1α stabilization using CHX to prevent protein synthesis. The HIF-1α protein was …

… This study aimed to examine the effect of the natural product vanillic acid (VA) on … Moreover,
VA downregulated the gene and protein expression levels of Hif-2α, Hif-1β, and Arg2 and …

… The effect of vanillic acid on HIF-1 activation was investigated in this study. In … lines, vanillic
acid inhibits HIF-1 expression caused by hypoxia. Vanillic acid prevented the synthesis of HIF-…

… Vanillic acid, as a bioactive substance, has also been demonstrated to have … is to target
hypoxia-inducible factor 1α (HIF-1α) using phenolic compounds. VA could downregulate HIF-1α …

… vanillic acid (VA) has shown anticancer potential in colon cancer by targeting mTOR/Ras
pathway, HIF-1α … been proposed that the combination of vanillic acid with oxaliplatin co-loaded …

… This study aimed to evaluate the cancer chemopreventive activity of vanillic acid (VA) in
diethylnitrosamine- and 1,2-dimethylhydrazine-induced liver and colon carcinogenesis in rats. …

… We found that vanillic acid (VA) could stimulate the STING/TBK1/IRF3 pathway. VA mediated
the production of type I IFN and promoted macrophage polarization into the M1 phenotype; …

… its effect on hypoxia-inducible factor 1 alpha (HIF-1α), which plays … Hispidulin modulates the
HIF-1α pathway by modulating … The inhibition of the HIF-1α pathway resulted in a decrease …

… In this study, we established a cancer–obesity comorbidity (COC) model to investigate the
effects of vanillic acid (VA). After a five-week administration with a high-fat diet (HFD) to induce …

… We selectively investigated the mechanism of action of the two most potent compounds
Vanillic acid (VA) and Epimedin C (Epi C). After identification of the anti-inflammatory and …