… integral role in the regulation of gene expression. This review focuses primarily … histone
deacetylases and deacetylase-containing complexes and their role in mediating transcriptional …

… on genome stability, transcriptional regulation, and … factors and transcription factors involved
in transcriptional repression in … the transcriptional repression mediated by HDACs in plants. …

… Disruption of histone deacetylase activity either by TPX or by direct mutation of a histidine …
site abrogates HDAC1-mediated transcriptional repression of a targeted reporter gene in vivo. …

… mSin3A-targeted repression of a reporter gene is reduced by trapoxin … that histone
deacetylation mediates transcriptional repression through Mad-Max-mSin3A multimeric complexes. …

… We have shown that the ligand-induced switch from transcriptional repression to … a histone
deacetylase-containing co-repressor complex for an activation complex that contains histone …

… Generation of Rpd3 mutants defective for histone deacetylase activity To investigate the
role of histone deacetylase activity in transcriptional repression by Rpd3, we wished to obtain …

… Significantly, both the Sin3 and Mi-2/NURD complexes also … deacetylation in a nontargeted
fashion. These results suggest that HDAC complexes can contribute to gene repression by …

… with a corepressor complex containing the transcriptional repressor mSin3A and histone
deacetylases 13,14,15,16,17,18,19 . Transcriptional repression in vivo is relieved by the …

… Given the unexpected association of a putative demethylase with transcriptional repression
complexes, we tested the demethylation activity of in vitro -translated mouse 4 or human 8 …

… region of mSin3A capable of mediating transcriptional repression. In addition, Mad1 forms a
… with histone deacetylases is sufficient for repression. Mad1 Forms a Ternary Complex with …