Cross-talk between the H3K36me3 and H4K16ac histone epigenetic marks in DNA double-strand break repair

L Li, Y Wang - Journal of Biological Chemistry, 2017 - ASBMB
Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining. …
that is characterized by its strong binding affinity toward methylated lysine in histone proteins ( …

H3K36me2 methyltransferase NSD2 orchestrates epigenetic reprogramming during spermatogenesis

Z Li, X Zhang, S Xie, X Liu, C Fei, X Huang… - Nucleic Acids …, 2022 - academic.oup.com
… , including histone modification alterations and histone-to-… predominant histone
methyltransferase catalyzing H3K36me2 … Nsd1 plays a critical role in de novo DNA methylation in …

H3K36me2/3 binding and DNA binding of the DNA methyltransferase DNMT3A PWWP domain both contribute to its chromatin interaction

M Dukatz, K Holzer, M Choudalakis, M Emperle… - Journal of molecular …, 2019 - Elsevier
… of DNMT3 DNA methyltransferases binds to histone H3 tails containing methylated K36, and
… Cellular DNA methylation experiments revealed that K36 methylation has a targeting effect …

De novo DNA methyltransferase activity in colorectal cancer is directed towards H3K36me3 marked CpG islands

RHA Masalmeh, F Taglini, C Rubio-Ramon… - Nature …, 2021 - nature.com
… de novo DNA methylation activity is targeted primarily to CpG islands marked by the histone
… A recent study demonstrates that Dnmt3a’s PWWP has greater affinity for H3K36me2 48 …

Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity

C Ballaré, M Lange, A Lapinaite, GM Martin… - Nature structural & …, 2012 - nature.com
… Unbiased analysis of Phf19-bound peaks showed an enrichment of H3K36me2 and … and
the H3K36me2 and H3K36me3 marks suggested that H3K36me2 and H3K36me3 histone

[HTML][HTML] The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSα

F Li, G Mao, D Tong, J Huang, L Gu, W Yang, GM Li - Cell, 2013 - cell.com
… This work reveals that a histone mark regulates MMR in human cells and explains the
long-standing puzzle of MSI-positive cancer cells that lack detectable mutations in known MMR …

[HTML][HTML] H3K36 methylation in neural development and associated diseases

M Zaghi, V Broccoli, A Sessa - Frontiers in Genetics, 2020 - frontiersin.org
… and DNA methylation. The homeostasis of H3K36 … for both di- (H3K36me2) and tri-methylation
(H3K36me3); H3K36me3 is … Mass spectrometry analyses of histone modifications have …

Set2 mediated H3 lysine 36 methylation: regulation of transcription elongation and implications in organismal development

S Venkatesh, JL Workman - Wiley Interdisciplinary Reviews …, 2013 - Wiley Online Library
… H3K36me1 and H3K36me2, also targets H4 K44 when methylating histone octamers but …
dependent histone turnover. DNA methylation as well as H3 K9 and H3 K27 methylation can …

Methylation of Histone H3 Lysine 36 Is Required for Normal Development in Neurospora crassa

KK Adhvaryu, SA Morris, BD Strahl, EU Selker - Eukaryotic cell, 2005 - Am Soc Microbiol
… to dim-5, which encodes a histone H3 lysine 9 HMT required for DNA methylation. We
demonstrate that Neurospora set-2 encodes a histone H3 lysine 36 (K36) methyltransferase and …

Histone H3K36 methylation regulates pre-mRNA splicing in Saccharomyces cerevisiae

MR Sorenson, DK Jha, SA Ucles, DM Flood… - RNA biology, 2016 - Taylor & Francis
… of histone modifications to pre-mRNA splicing in Saccharomyces cerevisiae, we probed a
library of histone … Nevertheless, our data suggests that H3K36me2 largely drives most of the …