Linking DNA methylation and histone modification: patterns and paradigms
H Cedar, Y Bergman - Nature Reviews Genetics, 2009 - nature.com
… Histone methylation can help to direct DNA methylation patterns, and DNA methylation
seems to serve as a template for rebuilding histone modification patterns following DNA …
seems to serve as a template for rebuilding histone modification patterns following DNA …
A shifting paradigm: histone deacetylases and transcriptional activation
CL Smith - Bioessays, 2008 - Wiley Online Library
… histones that occurs upon normal activation of the c-jun promoter(45) but, rather, it mimicked
this pattern, indicating that increased histone … -wide patterns of histone modifications in yeast…
this pattern, indicating that increased histone … -wide patterns of histone modifications in yeast…
Histone modification: cause or cog?
S Henikoff, A Shilatifard - Trends in Genetics, 2011 - cell.com
… based on correlation and that patterns of some key histone modifications are more easily …
of histone modifying enzymes. We suggest that the 35-year-old DNA accessibility paradigm …
of histone modifying enzymes. We suggest that the 35-year-old DNA accessibility paradigm …
Roles of histone deacetylases in epigenetic regulation: emerging paradigms from studies with inhibitors
… discovered on histones, is a dynamic posttranslational modification (PTM) regulated by
the opposing activities of lysine acetyltransferases (KATs) and histone deacetylases (HDACs). …
the opposing activities of lysine acetyltransferases (KATs) and histone deacetylases (HDACs). …
Current paradigms in epigenetic anticancer therapeutics and future challenges
… understanding DNA methylation and histone modifications during transcription of … histone
modifying enzymes including DNA methyltransferase (DNMT) enzyme inhibitors and a histone …
modifying enzymes including DNA methyltransferase (DNMT) enzyme inhibitors and a histone …
Charting histone modifications and the functional organization of mammalian genomes
VW Zhou, A Goren, BE Bernstein - Nature Reviews Genetics, 2011 - nature.com
… the types and patterns of histone modifications that have … , and have revealed important
paradigms of gene regulation. … LCPs have different histone modification patterns and distinct …
paradigms of gene regulation. … LCPs have different histone modification patterns and distinct …
5-azacytidine treatment reorganizes genomic histone modification patterns
VM Komashko, PJ Farnham - Epigenetics, 2010 - Taylor & Francis
… by histone modifications, we first identified promoters that had high levels of H3K27me3 and
H3K9me3 in the control cells and then determined the levels of these modified histones on …
H3K9me3 in the control cells and then determined the levels of these modified histones on …
Interpreting the language of histone and DNA modifications
SB Rothbart, BD Strahl - Biochimica et Biophysica Acta (BBA)-Gene …, 2014 - Elsevier
… : Molecular mechanisms of histone modification function. … histone PTMs, the co-existence
of histone modifications has … the short and long-range histone PTM combinations that occur. …
of histone modifications has … the short and long-range histone PTM combinations that occur. …
Discovering common combinatorial histone modification patterns in the human genome
C Linghu, H Zheng, L Zhang, J Zhang - Gene, 2013 - Elsevier
… To identify common combinatorial histone modification patterns that frequently co-occur in …
the concept of histone modification patterns. Let g ij be a tag dataset of histone modifications, …
the concept of histone modification patterns. Let g ij be a tag dataset of histone modifications, …
Histone-net: a multi-paradigm computational framework for histone occupancy and modification prediction
… , and histone altering enzymes [21], histone modification detection is essentially required [22].
Histone modifications [23] … Histone octamers repeat themselves across all nucleosomes in …
Histone modifications [23] … Histone octamers repeat themselves across all nucleosomes in …
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