… histone and DNA methyltransferases. We then discuss how histone modification and DNA
methylation can have different roles in gene silencing, with histone modifications providing …

… with important histone post-translational modifications. Moreover… DNA methyltransferases
(DNMTs) that contribute to the crosstalk between DNA methylation and chromatin modifications…

… term epigenetic modification … DNA sequences in vertebrates often have little or no methylation.
The methylation of mammalian genomic DNA is catalyzed by DNA methyltransferases (…

… with other histone modifications. Our finding that a DNA methyltransferase can contact H3‐…
of H3 might function in concert with DNA methylation to repress transcription. By analogy to …

… the histone modification status at … modifications were low, and no statistical difference
between the two cell lines was found. This result suggested that alteration of histone modification …

… Among the various forms of epigenetic modifications, DNA methylation at the C-5 position of
… of the most well studied epigenetic modifications. DNA methyltransferases (DNMTs) are a …

… -marking system that operates at the level of histone modification. This article reviews
recent studies on, and discusses the resulting biochemical and structural insights into, the …

… DNA methylation influences the histone modification pattern. For instance, early observations
showed that components of the DNA methylation machinery (ie DNA methyltransferases […

… Very recently, one study identified a new de novo DNA methyltransferase DNMT3C in murine
… The relationship between DNA methylation and histone modification should provide more …

… shown to bind to specific modified histones (reviewed in [39]). … histones or histone modifications.
While purified DNMT1 does have a modest intrinsic preference for hemimethylated DNA …