Reversible covalent histone modifications are known to influence spatiotemporal patterns of
gene transcription during development. Here I review recent advances in the development
and use of methods to analyze the distribution and functions of histone modifications in
zebrafish chromatin. I discuss the roles of dynamic histone modification patterns at the
promoters and enhancers of genes during the process of zygotic gene activation at blastula
stages and the interplay between the molecular machinery responsible for histone …