[HTML][HTML] Concordant and discordant DNA methylation signatures of aging in human blood and brain
… We took advantage of published datasets to evaluate the reproducibility of our findings of
tissue-concordant and tissue-discordant DNA methylation signatures of aging. We used the …
tissue-concordant and tissue-discordant DNA methylation signatures of aging. We used the …
[HTML][HTML] DNA methylation signatures in peripheral blood strongly predict all-cause mortality
Y Zhang, R Wilson, J Heiss, LP Breitling… - Nature …, 2017 - nature.com
DNA methylation (DNAm) has been revealed to play a role in various diseases. Here we
performed epigenome-wide screening and validation to identify mortality-related DNAm …
performed epigenome-wide screening and validation to identify mortality-related DNAm …
[PDF][PDF] Anatomy of DNA methylation signatures: Emerging insights and applications
E Chater-Diehl, SJ Goodman, C Cytrynbaum… - … Journal of Human …, 2021 - cell.com
… While DNA methylation signatures have demonstrated … DNA methylation signatures in full,
ie, all CpG sites used in the predictive models, to allow any reader to validate the signature for …
ie, all CpG sites used in the predictive models, to allow any reader to validate the signature for …
[HTML][HTML] Identification of a DNA methylation signature in blood cells from persons with Down Syndrome
MG Bacalini, D Gentilini, A Boattini, E Giampieri… - Aging (Albany …, 2015 - ncbi.nlm.nih.gov
… BeadChip to investigate DNA methylation patterns in whole blood from 29 … DNA methylation
patterns deriving from genetic and environmental factors. Although differentially methylated …
patterns deriving from genetic and environmental factors. Although differentially methylated …
[PDF][PDF] DNA methylation signatures within the human brain
C Ladd-Acosta, J Pevsner, S Sabunciyan… - … Journal of Human …, 2007 - cell.com
… Our data suggest that DNA methylation signatures distinguish brain regions and may … DNA
methylation signature that distinguishes three human brain regions. These brain methylation …
methylation signature that distinguishes three human brain regions. These brain methylation …
Whole blood DNA methylation signatures of diet are associated with cardiovascular disease risk factors and all-cause mortality
J Ma, CM Rebholz, KVE Braun… - Circulation: Genomic …, 2020 - Am Heart Assoc
… between peripheral blood-derived DNA methylation profiles and those from other tissues,
we lacked data to analyze tissue-specific diet-associated DNA methylation changes which …
we lacked data to analyze tissue-specific diet-associated DNA methylation changes which …
[HTML][HTML] Blood-based DNA methylation signatures in cancer: A systematic review
Y Li, Z Fan, Y Meng, S Liu, H Zhan - … Acta (BBA)-Molecular Basis of Disease, 2023 - Elsevier
… The present paper summarizes the changes in DNA methylation in cancer based on existing
research and focuses on the characteristics of the detection objects of blood-based DNA, …
research and focuses on the characteristics of the detection objects of blood-based DNA, …
[HTML][HTML] DNA methylation signatures of autoimmune diseases in human B lymphocytes
M Zouali - Clinical Immunology, 2021 - Elsevier
… In studies of complex human diseases, initial studies compared differences in DNA
methylation in whole peripheral blood between cases and controls. However, this strategy makes …
methylation in whole peripheral blood between cases and controls. However, this strategy makes …
[HTML][HTML] DNA methylation signature in peripheral blood reveals distinct characteristics of human X chromosome numerical aberrations
A Sharma, MA Jamil, N Nuesgen, F Schreiner… - Clinical …, 2015 - Springer
… It is known that blood lymphocytes are central in adaptive immune responses. Thus, it …
methylation signature enriched with major immune response factors from studying relevant blood …
methylation signature enriched with major immune response factors from studying relevant blood …
DNA methylation signatures in blood DNA of Hutchinson–Gilford Progeria syndrome
… -wide DNA methylation signatures in whole blood DNA of progeroid laminopathy patients
with LMNA mutations versus age- and gender-matched controls. Differentially methylated sites …
with LMNA mutations versus age- and gender-matched controls. Differentially methylated sites …
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