Distinct DNA methylation changes highly correlated with chronological age in the human brain

DG Hernandez, MA Nalls, JR Gibbs… - Human molecular …, 2011 - academic.oup.com
… distinct brain regions, … age on DNA methylation status in human brain. We find that there
is a strong and significant correlation between CpG methylation and aging of the human brain

Differences between chronological and brain age are related to education and self-reported physical activity

J Steffener, C Habeck, D O'Shea, Q Razlighi… - Neurobiology of …, 2016 - Elsevier
… Scatter plot of chronological age versus brain age in years after adjusting for nuisance
variables. The solid line is the regression fit between the 2 variables, and the dashed lines are 1 …

Brain age and other bodily 'ages': implications for neuropsychiatry

JH Cole, RE Marioni, SE Harris, IJ Deary - Molecular psychiatry, 2019 - nature.com
… ’ the relationship between age and brain structure in large samples of healthy adults. Model
performance, evaluated by predicting chronological age based on brain scans from new …

Cellular senescence and chronological age in various human tissues: a systematic review and meta‐analysis

CSL Tuttle, MEC Waaijer, MS Slee‐Valentijn… - Aging cell, 2020 - Wiley Online Library
… The highest magnitude of senescence per 10 years of age was observed in brain (β = 6.23
± 0.55 SU) and adipose (β = 1.88 ± 0.24 SU) tissue. Similarly, senescence markers identified …

Prediction of chronological age in healthy elderly subjects with machine learning from MRI brain segmentation and cortical parcellation

J Gómez-Ramírez, MA Fernández-Blázquez… - Brain Sciences, 2022 - mdpi.com
… predictor of chronological age is the brain-to-intracranial-volume ratio, followed by the
hippocampi volume. Thirdly, the thickness of sulci is more important in predicting age than the …

[HTML][HTML] Brain aging in temporal lobe epilepsy: Chronological, structural, and functional

G Hwang, B Hermann, VA Nair, LL Conant, K Dabbs… - NeuroImage: Clinical, 2020 - Elsevier
… The predicted ages (brain ages) were compared to the chronological ages. Accelerated
ages (brainchronological ages) were calculated. The entire training and testing process is …

Reaction time and chronological age

CJ Bellis - Proceedings of the Society for Experimental …, 1933 - journals.sagepub.com
Although the literature dealing with reaction time is enormous, no studies seem to have
appeared of the relationship between reaction time and chronological age in a large group of …

T1 white/gray contrast as a predictor of chronological age, and an index of cognitive performance

…, J Tohka, Brain Development Cooperative Group - Neuroimage, 2018 - Elsevier
… We define the age residual as chronological age minus predicted age. Again, we considered
the data as cross-sectional, taking care to ensure that the longitudinal data did not bias the …

Chronological age and its impact on associative learning proficiency and brain structure in middle adulthood

VA Diwadkar, M Bellani, R Ahmed, N Dusi… - Behavioural Brain …, 2016 - Elsevier
age-related changes in middle-adulthood. In this investigation we assessed the effects of
chronological age … matter volume estimated using a whole brain voxel based morphometry. In …

An in vivo study on brain microstructure in biological and chronological ageing

I Altmann-Schneider, AJM de Craen… - Plos one, 2015 - journals.plos.org
… Differences in age were tested using independent samples t-tests. MTI measures of all brain
… assess the association of brain tissue MTI parameters with chronological age, adjusted for …